氩离子凝固术治疗早期食管癌及癌前病变52例的疗效分析  

Clinical research of diagnostic and therapeutic value of endoscopy for early esophagus carcinoma and precancerous lesions in 52 cases

作　　者：张旭东[1] 吴天清[1] 张春玲[1] 周宇[1] 郑桂香[1] 

机构地区：[1]三台县人民医院,四川三台621100

出　　处：《现代医药卫生》2011年第10期1490-1491,共2页Journal of Modern Medicine & Health

摘　　要：目的:探讨内镜下对早期食管癌及癌前病变的诊断与治疗价值。方法:对我院消化内科收治的52例常规内镜下行碘染色及病理活检诊断早期食管癌及癌前病变患者52例,其中食管鳞状细胞原位癌29例、食管鳞状上皮重度不典型增生23例,应用氩离子凝固术(argon plasma coagulation,APC)治疗。结果:术中创面出血4例,术后出血3例,经内镜下治疗或保守治疗均成功止血;无穿孔、狭窄等并发症发生;所有患者术后2、6、12个月随访,内镜复查,治疗成功率为92.5%,4例分别在术后6、7、9个月复发,再行APC治疗。结论:APC是治疗的早期食管癌及癌前病变重要方法。Objective：To study the clinical value of endoscopic argon plasma coagulation in detection and treatment of early esophagus carcinoma and precancerous lesions.Methods：52 cases of early esophagus carcinoma and precancerous lesions diagnosed by iodine staining under conventional endoscopy and pathological biopsy were admitted to the department of gastroenterology in our hospital from January 2008 to July 2010,including 29 cases of esophageal squamous cell carcinoma in situ and 23 cases of severe esophageal squamous dysplasia,and given argon plasma coagulation（APC） treatment.Results：4 cases of intraoperative wound bleeding and 3 cases of postoperative bleeding were achieved successful hemostasis by endoscopic hemostasis or conservative treatment.No case of perforation,stenosis and other complications occurred.All the patients were followed-up for 2,6,12 months and rechecked by endoscopy with the treatment success rate of 92.5%.4 cases relapsed in postoperative 6,7,9 months and received APC treatment again.Conclusion：APC is the important treatment method of early esophageal cancer and precancerous lesions.

关 键 词：氩离子凝固术 早期食管癌 癌前病变 诊断 治疗 

分 类 号：R73[医药卫生—肿瘤]