青年与中老年胃癌临床病理学特征及临床意义  

Analysis of clinicopathologic difference between carcinoma of stomach in the young patients and in the elder patients

作　　者：程慧敏[1] 王少卿[1] 王鹏程[1] 唐彩白 王旭波[1] 沈桂清[1] 田兆伦 王颖[1] 

机构地区：[1]徐州医学院第二附属医院

出　　处：《中国肿瘤临床与康复》1999年第5期43-45,共3页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的探讨青年胃癌与中老年胃癌的临床病理学特征并讨论其相应的临床意义。方法应用病理组织学与组织化学、免疫组化以及18项临床病理学因素分析了手术切除的16例青年胃癌以及227例中老年胃癌的临床病理学特征，并比较两者在临床病理学方面的差异。结果青年胃癌在性别、组织类型、肿瘤区微血管类型与数量、淋巴管侵袭、淋巴结转移、神经纤维周围侵袭及腹腔播散等方面与中老年胃癌相比具有显著差异；而在肿瘤部位、肉眼类型、侵犯深度、TNM分期、幽门螺杆菌感染、静脉侵袭、淋巴组织反应、间质反应、复发及肝转移方面无显著差异。结论综合分析青年胃癌与中老年胃癌之间所呈现的具有显著性差异的临床病理学因素，对于判定青年胃癌的临床病理学特征，指导治疗及推测手术预后具有重要意义。Objective To investigate the difference of clinicopathologic features between carcinomas of stomach in the young patients (less than 40 years) and in the elder patients (aged 40 to 82) and to evaluate its significance. Methods Clinicopathologic factors were analyzed in the gastrectomy specimen of gastric cancer in 16 young patients and 227 older patients by pathologic,immunhistochemical and histochemical examinations. Results Carcinomas of stomach in the young patients were mainly associated with sex, histologic classification, microvascularity in tumor tissues. lymphatic invasion. lymph node involvement, neurofiber invasion, intraabdominal spreading rather than tumorlocalization of gastric carcinoma, gross appearance, depth of infiltration,TNM stage, infection of Helicobacter pylon,venous invasion, lymphatic reaction, interstitial reaction, recurrence of gastric cancer and hepatic metastasis. Conclusion Clinicopathologic analysis had significant value in judging recurrence and prognosis of patients with gastric cancer in young patients.[

关 键 词：青年 胃癌 中老年 临床病理 

分 类 号：R735.202[医药卫生—肿瘤]