Stereoselective Synthesis of 1-Aminocyclopropanecarboxylic Acid Derivatives via Ylide Cyclopropanation of Dehydroamino Acid Derivatives  

作　　者：周锐 邓贤明 郑君成 沈琪 孙秀丽 唐勇 

机构地区：[1]Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Ma- terials Science, Soochow University, Suzhou, Jiangsu 215123, China [2]State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, 345 Lingling Lu, Shanghai 200032, China

出　　处：《Chinese Journal of Chemistry》2011年第5期995-1000,共6页中国化学（英文版）

基　　金：Project supported by the National Natural Science Foundation of China （Nos. 20821002, 20932008）, the Major State Basic Research Development Program （No. 2009CB825300）, and the Science and Technology Commission of Shanghai Municipality （No. Y0D00512E0）.

摘　　要：1-Aminocyclopropanecarboxylic acid derivatives are synthesized from readily available dehydroamino acid de- rivatives via sulfur ylide. A range of different ylides are employed and the corresponding aminocyclopropanes are afforded with reasonable diastereoselection in good yields.1-Aminocyclopropanecarboxylic acid derivatives are synthesized from readily available dehydroamino acid de- rivatives via sulfur ylide. A range of different ylides are employed and the corresponding aminocyclopropanes are afforded with reasonable diastereoselection in good yields.

关 键 词：amino acids ENANTIOSELECTIVITY ANNULATION YLIDES stereoselective synthesis 

分 类 号：O624.11[理学—有机化学] TQ453.4[理学—化学]