黄斑部结节性脉络炎的吲哚青绿血管造影  

INDOCYANINE GREEN ANGIOGRAPHY IN NODULAR MACULAR CHORO IDITIS

作　　者：李敏[1] BarbaraSMTam 张琳 MarkOMTso 

机构地区：[1]广西壮族自治区人民医院,南宁530021 [2]香港中文大学眼科和视觉科学学系

出　　处：《广西医科大学学报》1999年第4期432-433,共2页Journal of Guangxi Medical University

摘　　要：目的 :用眼底荧光血管造影 ( Fundus fluorescein angiography,FFA )和吲哚青绿血管造影 ( Indocyanine greenangiography,ICGA)观察黄斑部结节性脉络膜炎 ( Nodular m acular choroiditis,NMC)的荧光特征。方法 :对 19例 2 1只 NMC患眼作裂隙灯眼底检查、 FFA及 ICGA检查 ,并对两种不同的眼底造影进行比较和分析。结果 :1活动期的 16只眼中 ,眼底均表现黄斑部黄白色隆起的结节 ,结节周围多伴有视网膜下出血及轻度渗出 ,FFA显示明显染料渗漏 ,而 ICGA早期表现为充盈迟缓 ,中晚期才见染料渗漏 ;2 3只眼在 FFA表现为单灶性渗漏而 ICGA则表现为多灶性渗漏 ;3 2只眼 ICGA晚期在结节处的强荧光斑外再出现一强度稍弱荧光环 ;4愈合期 5只眼中 ,眼底表现为伴有色素沉着的视网膜下疤痕 ,FFA及ICGA显示这些部位表现为低荧光或着染。结论 :活动期的 NMC,ICGA能更准确显示病灶大小 ,并能显示Objective:To detect and monitor the features of nodular macular choroiditis (NMC) by using slit lamp and +90D lens,fundus fluorescein angiography (FFA) and indocyanine green angiography (ICGA).Methods:19 subjects (21eyes) were recruited in this study Slitlamp and fundal examination were performed on these subjects They all underwent both FFA and ICGA The results of FFA were then compared with those from ICGA Results:①During active stage of NMC,16 eyes showed white to yellow elevated nodular lesions in the macula The nodule was often accompanied by surrounding subretinal hemorrhage and mild exudation In these cases,FFA showed early leakage;in contrast,ICGA showed delay filling of the dye in the nodular area,but leakage in middle and late phases ② In 3 eyes,ICGA showed multiple leakage but FFA showed one area of leakage ③ In 2 eyes,ICGA detected a thin hypofluorescent ring around the nodule This in turn was surrounded by another hyperfluorescent ring in late phase of ICGA ④ In the healing stage,5 eyes showed subretinal gliosis with pigmentation of the original nodular lesion In both FFA and ICGA,these areas were hypofluorescent and some showed late staining Conclusion:① In the active stage of NMC,ICGA was superior than FFA in judging the presence and range of NMC and indicated a neovascular lesion was present ② ICGA was able to detect smaller areas of leakage when compared with FFA These lesions may not be detected by fundal examination

关 键 词：结节性脉络膜炎 黄斑部 眼底荧光摄影 FFA ICGA 

分 类 号：R773.404[医药卫生—眼科] R770.43[医药卫生—临床医学]