新型周期性细胞压缩牵张仪的研制与应用  

Development and application of novel cellular cyclic tension and compression apparatus

作　　者：钟喆[1] 张正朴 曾祥龙[1] 

机构地区：[1]北京大学口腔医学院正畸科,100081 [2]杭州奥杰医疗器材有限公司

出　　处：《现代口腔医学杂志》2011年第3期170-173,共4页Journal of Modern Stomatology

基　　金：国家自然科学基金项目(30772452)

摘　　要：目的设计制作一种新型细胞加载系统,能在相同条件下对细胞施加压缩应力或者牵张应力。方法利用弹性膜片应力应变呈线性关系的原理,进行细胞加力装置和微电脑运动控制器的设计。结果设计的细胞加载系统可精确控制施加应力大小和频率,初步的细胞加载试验表明设计达到预期效果。结论利用此新型周期性细胞压缩牵张仪建立的细胞加载模型,可模拟口腔正畸临床中,牙槽骨一侧细胞受压,一侧细胞受牵张的现象。Objective To develop a novel cell mechanical loading system which could compress or stretch cells under the same condition.Methods Based on the principle that the strain-stress relationship of elastic membrane is linear,we designed the cellular cyclic tension and compression apparatus（CCTCA）.Results In the primary cell loading experiments,CCTCA demonstrated stable and reliable mechanical property which met the system conditional defaults.Conclusion With this novel system we can establish a cell mechanical loading model which mimics the phenomenon in orthodontic practice in which cells in one side of the alveolar bone are stretched while those in the other side compressed.

关 键 词：周期性细胞压缩牵张仪 压缩应力 牵张应力 

分 类 号：R783.5[医药卫生—口腔医学]