低级别胶质瘤继发癫痫的手术治疗  

The surgical treatment of low - grade glioma with secondary epilepsy

作　　者：郭韬[1] 康进生[1] 杜亚丽[1] 武江[1] 董长征[1] 岳向勇[1] 李文玲[1] 赵文清[1] 

机构地区：[1]河北省人民医院功能神经外科,石家庄050051

出　　处：《中华神经外科杂志》2011年第5期554-557,共4页Chinese Journal of Neurosurgery

摘　　要：目的探讨低级别胶质瘤继发癫痫的手术治疗方法。方法采用视频脑电、脑磁图定位致痫灶、功能区，手术中联合应用立体定向引导、术中B超、术中皮质电刺激等技术治疗继发癫痫的低级别胶质瘤13例。结果全部患者在手术切除、保护神经功能的同时，控制了癫痫发作，临床效果良好。结论多种定位技术的联合应用，可在最大程度切除肿瘤、致痫灶的同时减少脑组织损伤，保留脑功能区皮质，控制癫痫发作，提高患者生活质量。Objective To explore the methods of surgical treatment of low - grade glioma with secondary epilepsy. Method Video-EEG,magnetoencephalography（MEG） were performed to localizated the epileptogenic zone and domain in 13 patients, and stereotactie technology, ultrasound, electrocorticogram （EcoG） were performed intraoperative combinating to treat the low-grade gliomas that lead to epilepsy. Results The seizure was controlled while the tumor was reseeted and the neural function were protected in all patients. The clinical effect was significant. Conclusions The combination of multiple technology to localize the epileptogenic can reseet the tumor or the epileptogenie zone maximum, reduce the injury of normal brain tissue, protect the cortex of brain domain, control the epileptic seizure and improve the patients＇ quality of life.

关 键 词：神经胶质瘤 低级别 癫痫 神经外科手术 

分 类 号：R739.4[医药卫生—肿瘤]