支架辅助栓塞治疗宽颈前交通动脉瘤的血管形态学改变研究  

Vascular morphological change due to endovascular stent placement for intracranial aneurysm

作　　者：黄清海[1] 吴永发[1] 刘建民[1] 许奕[1] 洪波[1] 张磊[1] 

机构地区：[1]第二军医大学长海医院神经外科,上海200433

出　　处：《中华神经外科杂志》2011年第5期566-569,共4页Chinese Journal of Neurosurgery

基　　金：国家自然科学基金（30901556）;上海市自然科学基金（08ZRl404200）

摘　　要：目的探讨支架辅助栓塞治疗宽颈前交通动脉瘤复合体血管形态改变及其对血流动力学的影响。方法15例宽颈前交通动脉瘤接受支架辅助弹簧圈栓塞治疗，在支架植入前后进行血管造影，并在二维影像上测量载瘤动脉流人段与流出段中轴线夹角，计算载瘤血管曲率变化。结果所有患者在支架植入后均有明显的载瘤动脉几何形态学改变。支架植入后载瘤血管夹角增加8．30°～53．06°，平均29．78°。7例患者支架植入后血管明显变直。结论支架植入可以明显改变宽颈前交通动脉瘤末梢血管几何形态学，进而可以导致局部血流动力学改变。Objective The purpose of this study was to quantify the vascular angle change due to intracrnaial stent placement and its effect on hemodynamics. Method Fifteen patients with a wide - necked anterior communicating artery aneurysm were treated with stent - assisted coiling. Centerlines of the parent vessels were calculated and determined the exact change in the vessel curvature in image underwent before and after stenting. Results In all patients, the stent caused a clear change in the geometry of the parent vessel. Stent - related vascular angle change ranged from 8.30 to 53.06 degrees, with an average of 29.78 degrees. In 7 cases the parent vessel was straightened. Conclusions Stents have a substantial effect on the vascular geometrv. resulting in a change in local hemodvnamics.

关 键 词：颅内动脉瘤 支架 介入 形态学 

分 类 号：R743[医药卫生—神经病学与精神病学]