乳腺癌胸壁照射时靶外组织受照剂量的研究  

Study on the Doses to the Tissues outside Field of Radiotherapy for Breast Cancer's Chest Wall with Electron-beams and X-rays

作　　者：涂彧[1] 姜德智[1] 周菊英[2] 秦颂兵 

机构地区：[1]苏州医学院放射医学系,苏州215007 [2]苏州医学院附属一院放疗科

出　　处：《苏州医学院学报》1999年第9期953-956,共4页Acta Academiae Medicinae Suzhou

摘　　要：探讨乳腺癌胸壁照射时，靶外组织的受照剂量。方法：借助非均匀组织等效拟人体模型，模拟左乳腺癌用９ Ｍｅ Ｖ 电子束和６ Ｍ Ｖ－ Ｘ 射线行胸壁照射，利用 Ｔ Ｌ Ｄ 测量靶外组织间接剂量。处方总剂量５０ Ｇｙ ，每次照射２ ．０ Ｇｙ 。９ Ｍｅ Ｖ 电子束照射时眼晶体、甲状腺、心脏、右肺、右后胸壁、右前胸壁、右乳、纵隔、左肺、左后胸壁、上腹部、下腹部、骨盆等处的受照总剂量为２９ ．０ ～２９５ ．５ｃ Ｇｙ ；６ Ｍ Ｖ－ Ｘ 射线照射时相应的受照总剂量为３２ ．０～２０６ ．７ｃ Ｇｙ ；阴影屏蔽可使电子束照射及 Ｘ 射线照射时靶外组织剂量分别下降９ ．４ ％ ～５３ ．６ ％ 和１９ ．７ ％ ～５６ ．６ ％ ；接触屏蔽可使 Ｘ 射线对靶外组织的剂量下降４４ ．２ ％ ～６０ ．８ ％ 。结论：采用电子束与 Ｘ 射线的不同的混合比照射对靶外组织的受照剂量有明显影响。Clinically relevant treatment fields were simulated on a tissue-equivalent material phantom and subsequently irradiated with 9Mev electron-beams and 6MV X-rays.TLD were used to measure absorbed doses. The prescribed dose was 50.0Gy,Each exposure dose was 2.0Gy.With 9MeV electron-beams,the doses exposed to lens of eye,thyroid gland,heart,right-lung,right-back-inner-chest wall,right-front-inner-chest wall,right-breast,mediastinum,left-lung,left-back-inner-chest wall,up-abdomen, down-abdomen and pelvis were from 29.0cGy to 295.5 cGy.When shielded with Pb lumps,the doses of the tissues outside the treatment field lowered by 9.4% ～53.6%.With X-rays,the doses of aforementioned tissues were from 32.0cGy to 206.7 cGy.When shielded with Pb lumps,the doses exposed to the tissues outside the treatment field lowered by 19.7%～56.6%.The doses exposed to the tissues outside field will be descended when mix-irradiation with electron-beams and X-rays.

关 键 词：乳腺癌 放射疗法 靶外剂量 体模 

分 类 号：R737.905[医药卫生—肿瘤] R730.55[医药卫生—临床医学]