肺癌、乳腺癌、食道癌远端骨转移特点的对比研究  

Comparative study between characteristics of the lung cancer, breast cancer and esophageal cancer distal bone metastases

作　　者：佟丽娟[1] 王明泽[3] 王丽梅[2] 

机构地区：[1]内蒙古通辽市医院核医学科,028000 [2]内蒙古通辽市医院瘤放疗科,028000 [3]青岛市第八人民医院,266100

出　　处：《国际放射医学核医学杂志》2011年第1期38-40,共3页International Journal of Radiation Medicine and Nuclear Medicine

摘　　要：【摘要】目的对比研究肺癌、乳腺癌、食道癌患者骨转移灶分布特点。方法对肺癌、乳腺癌、食道癌患者454例进行^99Tc^m-亚甲基二膦酸盐（^99Tc^m-MDP）SPECT全身骨显像，以上肢中远端和（或1骨盆、下肢部位发生骨转移为纳入条件，分析骨转移灶的分布特点及其在病种间的区别。结果454例肿瘤患者中，上肢中远端和（或）骨盆、下肢有异常放射性浓聚者120例，共发现骨转移灶1303个，其中，肺癌共有839个转移灶（64．4％），乳腺癌共有361个转移灶（27．7％），食道癌共有103个转移灶（7．9％）。在股骨的浓聚灶中，各病种发生在大小转子区的放射性浓聚灶所占比例较大。结论^99Tc^m-MDP全身骨显像显示，肺癌、乳腺癌、食道癌骨转移灶的分布在不同部位有所不同。Objective To compare the characteristics of the distribution of bone metastases in lung cancer, breast cancer and esophageal cancer. Methods SPECT bone imaging of the entire body was performed after the injection of ^99Tc^m-methylene diphosphonate （^99Tc^m-MDP） in 454 cases. Analyzed the distribution of metastatic bone lesions in upper limbs ＇middle and distal or the pelvis and lower limbs and the distinction of metastatic bone lesions between different diseases were distinguished. Results Of all the 454 patients, 120 cases showed abnormal radionuclide concentration in the region of upper limbs＇ middle and distal or the pelvis and lower limbs. One thousand three hundreds and three metastatic bone lesions were found in all the patients [893 were in lung cancer（64.4%）, 361 were in breast cancer （27.7%） and 103 were in esophageal cancer （7.9%） ]. Radioactive uptake in rotor area of femur lesions in these diseases was demonstrated to be of large proportion. Conclusions The result of ^99Tc^m-MDP bone imaging shows that the distribution of the metastatic bone lesions in lung cancer, breast cancer and esophageal cancer vary from place to place.

关 键 词：肺肿瘤 乳腺肿瘤 食道肿瘤 肿瘤转移 ^99Tc^m-美罗酸盐 全身显像 

分 类 号：R730.2[医药卫生—肿瘤]