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作 者:叶文亭[1] 张妮[1] 杨晓春[1] 钟丽梅[1] 丁雪梅[1]
机构地区:[1]广东省深圳市宝安区西乡人民医院,广东深圳518102
出 处:《中国医药导报》2011年第17期16-18,共3页China Medical Herald
基 金:深圳市宝安区科技计划社会公益科研资助项目;深宝科[2009]30号(项目名称:内镜下消化疾病血流动力学与中医脉象的关系;项目编号:2009439)
摘 要:目的:探讨内镜下消化疾病血流动力学与中医脉象的关系。方法:选择本院消化疾病患者1 150例及健康干部体检者150例(对照组)。采用临床分析比较与数据统计的方法对内镜下消化疾病患者血流动力学及其中医脉象进行对比研究,探讨两者之间的联系。结果:消化疾病患者中医脉象表现与消化内镜下诊断完全一致占75.57%,基本一致占19.21%,总准确率为94.78%。与对照组比较,各种消化疾病组每搏输出量(SV)、心脏指数(CI)、左室射血时间(LVET)、动脉顺应性(AC)均减小(P<0.01);射血前期(PEP)、总外周阻力(TPR)增大(P<0.01);在食管、胃及十二指肠、大肠黏膜各类消化疾病中,溃疡性疾病比一般炎症疾病SV、CI减小(P<0.05)。结论:消化疾病的病变过程与心肌收缩力、心输出量、动脉顺应性呈负相关性,与总外周阻力呈正相关性,这也许是消化疾病的脉象的血流动力学基础。Objective: To observe the relationship between hemodynamics and Traditional Chinese Medicine(TCM) pulse conditions in digestive diseases by endoscopy.Methods: 1 150 patients with digestive disease and 150 healthy cadres(control group) who have received physical examination in our hospital were collected.The clinical analytic comparison and statistics methods were used for the comparative study of hemodynamics and TCM pulse conditions in digestive diseases by endoscopy and for investigation of the relationship between them.Results: Patients with digestive diseases whose TCM pulse conditions were exactly the same as the diagnosis by endoscope accounted for 75.5%,and those basically the same accounted for 19.21%.The total accuracy was 94.78%.Compared with the control group,stroke volume(SV),cardiac index(CI),left ventricular ejection time(LVET) and arterial compliance(AC) reduced in groups with all sorts of digestive diseases(P〈0.01) while pre-ejection period(PEP) and total peripheral resistance(TPR) increased(P〈0.01).SV and CI of ulcerative diseases decreased compared with general inflammatory diseases in digestive diseases of esophageal,gastric,duodenal and escherichia mucosa(P〈0.05).Conclusion: The development of digestive diseases is in positive correlation with myocardial contractility,cardiac output and arterial compliance while in negative correlation with total peripheral resistance.It is supposed that this may be the hemodynamics basis of TCM pulse conditions in digestive disease.
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