青年人大肠癌的临床病理特征及预后分析  

Clinicopathological features and prognosis analysis in young patients with colorectal cancer

作　　者：任于晗 钟芸诗[2] 姚礼庆[2] 

机构地区：[1]浙江省嵊州市人民医院消化科,浙江嵊州312400 [2]复旦大学附属中山医院,上海200032

出　　处：《中国内镜杂志》2011年第5期457-459,463,共4页China Journal of Endoscopy

摘　　要：目的探讨青年人(年龄<30岁)大肠癌的临床病理特征及预后。方法总结分析复旦大学附属中山医院1109例青年人大肠癌患者的临床特点、病理特征和生存率。结果 1109例患者的平均病程(6.5±7.8)个月,误诊575例,占51.8%,以误诊为肠炎、痔疮、痢疾多见。TNM分期Ⅲ、Ⅳ期共1025例,占92.5%。病理类型以低分化腺癌、未分化癌、黏液腺癌、印戒细胞癌多见,共614例,占55.3%。1109例患者中611例(55.1%)行根治性手术,根治组5年随访生存率18.9%。结论青年人大肠癌误诊率高,恶性程度高,预后差。如何早诊和早治是提高生存率的关键。[Objective] To study the clinicopathological features and survival rate in young patients （age30） with colorectal cancer. [Methods] Applying statistic methods, we analyzed the clinicopathological features and survival rate of 1109 cases of young patients with colorectal cancer in Zhongshan Hospital, Fudan University. [Results] The mean duration from onset of symptoms to diagnosis in this group was （6.5±7.8） months. 575/1109 were misdiagnosed. The misdiagnosis rate was 51.8%. They were often misdiagnosed as bacillary dysentery, hemorrhoid and enteritis. TNM stages III and IV was noted in 1025 cases （92.5%）. The proportion of poorly differentiated adenocarcinoma, undifferentiated carcinoma, mucinous carcinoma and signet-ring cell carcinoma was 55.3%. The 5-year survival rate in complete resection group was 18.9%. [Conclusion] The young patients with colorectal cancer have the characteristics of high misdiagnosis rate, high incidence of poor differentiation, more advanced stages and poor prognosis.In order to raise the survival rate, it is important for us to diagnose and treat the young adults with colon cancer as early as we can.

关 键 词：大肠癌 青年人 临床特征病理 预后 

分 类 号：R735.34[医药卫生—肿瘤]