MRI对原发性中枢神经系统淋巴瘤的诊断  

MRI Diagnosis of Primary Central Nervous System Lymphoma

作　　者：向超[1] 李茂[1] 

机构地区：[1]广西医科大学第一附属医院放射科,广西南宁530021

出　　处：《实用放射学杂志》2011年第5期666-669,共4页Journal of Practical Radiology

摘　　要：目的 探讨原发性中枢神经系统淋巴瘤（primary central nervous system lymphoma,PCNSL）的MRI特点,提高对PCNSL的认识和诊断水平.方法 回顾性分析21例经手术病理或穿刺活检证实的PCNSL的MR表现,并结合文献研究MRI特征.结果 单发7例,多发7例,弥漫性生长7例,共33个肿瘤,其中额叶12个,脑室旁8个,颞叶、顶叶、透明隔、小脑蚓部各2个,枕叶、基底节区、丘脑、脑干、小脑各1个; 4例肿瘤累及胼胝体.肿瘤实质MR T1WI呈等或稍低信号,T2WI呈等或稍高信号,信号较均匀;18例肿瘤实质强化明显,信号均匀,可呈现＂尖角征＂和＂脐凹征＂及具有特征性的＂蝴蝶征＂,3例出现环形强化.结论 PCNSL MR检查具有特征性表现,MRI检查对PCNSL具有独特的诊断价值.Objective To discuss the MRI features of primary central nervous system lymphoma（PCNSL） ,so that to improve its diagnostic knowledge. Methods MRI features in 21 patients with pathologically confirmed PCNSL were analyzed retrospectively. All patients underwent plain and contrast-enhanced MR examination. Results The lesions were single, multiple and diffuse in 7 cases respectively, there were tolally 33 lesions. The lesions located in frontal lobe in 12, periventricular area in 8, temporal lobe, parietal lobe, septum pellucidum and vermis in 2 respectively,occipital lobe, basal ganglia, thalamus, brainstem and cerebellum in one respectively, corpus callosum in 4 cases. The tumoral parenchyma demonstrated iso-or mild low signal intensity on T1 WI ans iso-or mild high signal intensity on T2 WI. The lesions in 18 cases demonstrated homogeneously marked enhancement with sharp border and showed specific feature of ＂cusp sign＂ , ＂dent sign＂ and specific feature of ＂butterfly sign＂,3 cases showed ring enhancement after injecting Gd-DTPA. Conclusion PCNSL has specific features on MRI. MRI has distinctively diagnostic value for PCNSL.

关 键 词：脑 原发性淋巴瘤 磁共振成像 

分 类 号：R739.41[医药卫生—肿瘤] R445.2[医药卫生—临床医学]