情感性精神障碍患者的睡眠脑电图试验研究  

An experimental study of polysomnogram in affective disorder

作　　者：陈兴时[1] 张明岛[1] 王继军[2] 严和骎[3] 徐琪珍[3] 楼翡缨 粱建华[1] 张怡[1] 

机构地区：[1]上海市精神卫生研究所,200030 [2]上海第二医科大学 [3]上海市精神卫生中心

出　　处：《中华精神科杂志》1999年第3期151-153,共3页Chinese Journal of Psychiatry

摘　　要：目的　探讨情感性精神障碍患者睡眠脑电图的特点。方法　对１０ 例躁狂症患者、１０ 例抑郁症患者的睡眠脑电图进行全夜测试，并与１６ 名正常受试者进行对照。结果　与对照组相比，抑郁症组睡眠脑电图改变主要有快眼动（ Ｒ Ｅ Ｍ） 睡眠潜伏期缩短等；躁狂症组实际睡眠时间减少，睡眠效率下降。两组比较，抑郁症组比躁狂症组 Ｒ Ｅ Ｍ 潜伏期更短。而躁狂症组比抑郁症组实际睡眠时间更少。结论　睡眠脑电图中的 Ｒ Ｅ Ｍ 指标有可能是情感性精神障碍患者所具有的特定生物学指标之一。Objective The goal of this study was to investigate the polysomnographic characteristics of patients suffering from affective disorder Methods The all night polysomnogram was recorded from 10 patients with depression, 10 with mania and 16 normal controls Results Compared with that of normal controls, the polysomnogram of depressive group presented a shorter REM latency, and the sleep time and sleep efficiency of manic group were decreased When the comparison was made between 2 patient groups, a shorter REM latency was also found with depression group, and less sleep time with mania group Conclusions A shorter REM latency of polysomnogram might be one biological marker of patients with affective disorder

关 键 词：情感障碍 脑电图 睡眠脑电图 

分 类 号：R749.404[医药卫生—神经病学与精神病学] R741.044[医药卫生—临床医学]