双表型急性白血病临床治疗分析  被引量:4

Clinical Analysis of Acute Leukemia Patients with Biphenotypic

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作  者:刘爱俊 

机构地区:[1]山东省平原县人民医院内三科,平原253100

出  处:《中国医药导刊》2011年第4期603-604,共2页Chinese Journal of Medicinal Guide

摘  要:目的:探究双表型急性白血病临床治疗效果的分析。方法:对我院66侧急性白血病患者进行MIC分型,采取流式细胞仪分析急性白血病的免疫表型,根据EGIL标准诊断为双表型急性白血病。结果:①双表型急性白血病较成年男性为多见,平均WBC为(48.0±75.6)×10^9L:②BAL以同时表达出髓系和B系抗原者最常见,占68.2%:③正常核型24例(36.4%),异常核型42例(63.6%),主要为R上阳性异常④51例患者行联合化疗法,完全缓解(CR)35例(68.6%)。讨论:双表型急性白血病发病率较小,但是一旦发病,治疗效果差,生存期短。Objective: To explore the clinical effect ofbiphenotypic acute leukemia.Methods: the data in 66 patients with acute leukemia patients MIC parting, adopt flow cytomettic analysis analysis with acute leukemia immunophenotype, according to EGIL standard diagnosed with acute leukemia double phenotype.Results: (1) biphenotypic acute leukemia is more common than adult males, the average WBC was (48.0 ±75.6) × 109L; (2) BAL to also express the myeloid and B lineage antigen are the most common, accounting for 68.2%; (3) normal karyotype (24 cases, 36.4%), abnormal karyotype in 42 cases (63.6%), mainly for the Rh-positive abnormal (4) 51 patients received combined chemotherapy, complete remission (CR) 35 cases (68.6%). Discussion: Biphenotypic acute leukemia, the incidence of small, but once the disease, treatment is poor, survival is short

关 键 词:急性白血病 双表型 临床特征 治疗方案 

分 类 号:R733.7[医药卫生—肿瘤]

 

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