胃楔形切除术致胃电节律改变的实验观察  

Observation and Research of Gastric Dysrhythmia after Gastric Wedge Resection

作　　者：张育瑆[1] 俞晓军[1] 考晓明[2] 黄云[3] 胡志前[1] 

机构地区：[1]第二军医大学附属长征医院普外科,上海200003 [2]南京军区总医院普外科,江苏南京210002 [3]中国人民解放军第413医院普外科,浙江舟山316000

出　　处：《现代生物医学进展》2011年第11期2049-2052,2070,共5页Progress in Modern Biomedicine

摘　　要：目的:观察楔形切除胃的不同部位对术后胃电节律的影响。方法:将30只雄性新西兰兔按照完全随机原则分为胃体近端楔形切除组、胃体远端楔形切除组及对照组3个处理组,每组10只。记录在自然恢复状态下术后3日、6日、9日胃体近端及胃窦处30分钟内慢波总数及正常慢波次数并计算正常慢波百分比。用析因设计分析切除部位、测量部位、术后时间三因素对胃慢波节律的影响。结果:上述三因素均对术后慢波节律有影响,切除胃体近端与切除胃体远端相比,前者引发的术后胃电节律紊乱的程度更严重且恢复更缓慢;术后测量胃窦处与测量胃体处相比,前者发生的胃电节律紊乱的程度更严重且恢复更缓慢。结论:大弯侧胃底与胃体交医院界处的"胃电起始区域"即为"胃电起搏区","胃电起搏区"的切除对术后胃电节律的影响大于传导区域切除对其影响。Objective： To observe the influence of wedge resecting the different site of stomach on postoperative gastric rhythm. Methods： Thirty male New Zealand white rabbits were randomly divided into three groups： proximal gastric corpus wedge resection group（n= 10）, distal gastric corpus wedge resection group（n= 10） and control group（n= 10）. At 3, 6, 9 days after operation without intervention, we recorded each rabbits the numbers of total Slow Wave and normal Slow Wave which were measured in proximal gastric corpus and gastric antrum and calculated normal range percent of Slow Wave. The relation of each factor （the site of resection, the site of meaurement and postoperative time） with the postoperative Slow Wave were analyzed by factorial design. Results： The above-mentioned three factors all had effect on the postoperative Slow Wave. Compared with distal gastric corpus wedge resection, Proximal gastric corpus wedge resection led to more severe gastric dysrhythmia and longer time to recover. Compared with proximal gastric corpus, Gastric dysrhythmia at gastric antrum was more severe and needed longer time to recover. Conclusion： ＂Gastric electrical initial region＂ at proximal gastric corpus is ＂Gastric pacing region＂. Wedge resecting Gastric pacing region has more influence on postoperative gastric rhythm than wedge resecting Gastric electric conduction region.

关 键 词：术后胃瘫综合症 胃电节律紊乱 胃电起搏区 胃楔形切除术 慢波电位 

分 类 号：Q953[生物学—动物学] R573[医药卫生—消化系统]