小儿急性脑水肿液体疗法(附2279例分析)  

Fluid therapy of acute brain edema in children (report of 2279 cases)

作　　者：金立明[1] 虞佩兰[1] 

机构地区：[1]湖南医科大学附属第一临床学院,410008

出　　处：《宁波医学》1999年第5期204-207,共4页

摘　　要：目的　观察第一线抗脑水肿制剂( 甘露醇、速尿、地塞米松) 及辨证地进行边补边脱液体疗法治疗小儿急性脑水肿的效果。方法　根据脑水肿协作组1988 年通过的小儿急性脑水肿诊断标准〔1〕进行早期诊断。自1990 年1 月至1997 年2 月,全国9 所医院,对小儿急性脑水肿2279 例,采用第一线抗脑水肿制剂及辨证地进行边补边脱液体疗法治疗。结果　病死率降低至17 .2 % 。结论　降低小儿急性脑水肿病死率与下列因素有关:①早期诊断及治疗;②正确使用第一线抗脑水肿制剂;Objective To observe the effect of the first-line anti-brain edema agents(mannitol, furosemide and dexamethasone) and the fluid therapy with “dehydration” and “replenishment” alternately to children with acute brain edema. Methods Early diagnosed the cases according to the diagnostic criteria of the brain edema in children of the cooperative group, 2279 children with acute brain edema were collected from 9 hospitals 1990-1997, all patients were treated with the first-line anti-brain edema agents and “dehydration ,fluid replenishment” therapy alternately instead of the previous restriction of fluid intaking. Results The mortality was reduced to 17.2% compared to previous groups. Conclusion The factors for reducing the mortality of children's acute brain edema were:(1) Early diagnosis and treatment; (2) Using the first-line anti-brain edema agents properly; (3) Applying dehydration and fluid replenishment individually.

关 键 词：儿童 脑水肿 液体疗法 脱水 补液 

分 类 号：R742.705[医药卫生—神经病学与精神病学] R748.05[医药卫生—临床医学]