扛板归抗肝纤维化作用的研究进展  

Research Progress in Antifirbotic Effects of Polygonum Perfoliatum L

作　　者：曹庆生[1] 陈光煜[1] 朱华[1,2] 

机构地区：[1]桂林医学院,广西桂林541001 [2]广西中医学院,南宁530001

出　　处：《医学综述》2011年第11期1680-1683,共4页Medical Recapitulate

摘　　要：肝纤维化是慢性肝病的共同病理改变,它不仅是慢性肝病向肝硬化发展的必经之路,而且贯穿于肝硬化的始终,甚至发展到肝癌。因此,对肝纤维化的研究已经成为目前我国乃至全世界研究的热门课题,以期阻断肝硬化和肝癌的发生,延缓疾病进程。对肝纤维化的治疗目前尚无特效药,近年研究显示中医药在肝纤维化的治疗方面具有很大优势,现主要对肝纤维化的发病机制、扛板归的成分、功能及扛板归与肝纤维化的关系等研究进展予以综述。Hepatic fibrosis（HF） is a common pathological process in chronic liver disease.HF is not only critical for the transition of chronic liver disease to cirrhosis,but also consistently accompanying liver cirrhosis,even progression into hepatocellular carcinoma.Therefore,the study on hepatic fibrosis has become a hot topic around China and the rest of the world at present,in aiming to interrupt the occurrence of cirrhosis and hepatocellular carcinoma and to delay disease procession.Currently there is no specific medicine for the treatment of hepatocellular carcinoma.Recent researches show that Chinese traditional medicine has great advantages in anti-fibrosis.This article summarizes the pathogenesis of hepatic fibrosis,composition of Perfoliatum perfoliatum L.,and the effects of Polygonum perfoliatum L.on hepatic fibrosis.

关 键 词：肝纤维化 发病机制 肝星状细胞 细胞因子 扛板归 

分 类 号：R363[医药卫生—病理学] R97[医药卫生—基础医学]