恶性肿瘤病人血液检查与临床分期及转移的相关性研究  

The associations between blood indexes with clinical pathological stages and metastasis conditions in malignant tumor patients

作　　者：赵晶[1] 游舟[1] 

机构地区：[1]四川省肿瘤医院普内科,四川成都610041

出　　处：《西部医学》2011年第6期1047-1049,共3页Medical Journal of West China

摘　　要：目的研究恶性肿瘤患者的血常规、凝血功能及血白蛋白、球蛋白等指标在不同分期及有无转移的情况下的差异及相关性,并探讨其临床意义。方法按不同分期及有无转移对胃癌、乳腺癌、食道癌、肾癌及肺癌等101例恶性肿瘤患者的血常规、凝血功能及血白蛋白、球蛋白等指标进行比较并进行相关性分析。结果恶性肿瘤不同分期各指标中红细胞、血红蛋白、FIB(纤维蛋白原)及白细胞计数有明显差异(P<0.05),其中FIB含量及白细胞计数与分期明显相关(r=0.244,P<0.05;r=0.220,P<0.05);在有及无转移的情况下仅白细胞计数的差异有统计学意义(P<0.05),且明显具有相关性(r=0.202,P<0.05)。结论 FIB及白细胞计数与恶性肿瘤患者的临床分期密切相关,且后者对于患者的预后具有预测价值。Objective To investigate the difference and relevance of complete blood count,coagulation test,albumin and globulins in different clinical pathological stages and metastasis conditions in patients with malignant tumors.Methods The complete blood count,coagulation test,albumin and globulins were compared and the relevant study was performed in patients of different clinical pathological stages and with or without metastasis.Results The different pathological stages,hemoglobin,red blood cell count,fibrinogen and white blood cell count were significantly different（P0.05）.The fibrinogen and white blood cell count were significantly relevant with clinical stages（r=0.244,P0.05 and r=0.220,P0.05）.The white blood cell count was significantly higher in patients with metastasis and was significantly relevant with it（r=0.202,P0.05）.Conclusion The fibrinogen and white blood cell count are significantly relevant with clinical pathological stages of malignant tumors,and white blood cell count is of prognostic values for them.

关 键 词：恶性肿瘤 纤维蛋白原 白细胞计数 

分 类 号：R73[医药卫生—肿瘤]