脑灰质异位症伴癫痫发作的临床表现及脑电图和影像学特征  

Study on Clinical Manifestation,EEG and Imaging in Patients with Gray Matter Heterotopia and Epilepsy

作　　者：王加强 冯凯[2] 王晓飞[3] 唐俊英[4] 

机构地区：[1]北京市顺义区张镇卫生院,101307 [2]北京市顺义区医院 [3]北京海淀医院 [4]首都医科大学宣武医院

出　　处：《中国全科医学》2011年第17期1922-1924,共3页Chinese General Practice

摘　　要：目的研究脑灰质异位症(gray matter heterotopia,GMH)伴癫痫发作的临床表现及脑电图和影像学特征。方法对我院临床确诊的14例GMH伴癫痫发作患者的临床资料进行回顾性分析,总结该病的临床表现及脑电图和影像学特点。结果 14例患者中部分性发作9例,其中继发全面性发作6例;全面性发作5例。3例智力低下。脑电图结果显示重度异常1例,中度异常8例,轻度异常5例。CT和(或)MRI显示:室管膜下GMH(subependymal GMH,SEH)4例,皮质下GMH(subcortical GMH,SCH)7例,带状GMH(band GMH,BH)1例,混合型GMH 2例。结论 GMH患者的癫痫发作以部分性发作多见。脑电图结果与影像学检查部位相符。Objective To study the clinical manifestations,EEG and imaging characters in patients with gray matter heterotopia and epilepsy.Methods Clinical data of 14 confirmed patients with GMH and epilepsy from our hospital were analyzed retrospectively,and then the clinical manifestations and imaging features were summarized.Results Of the 14 patients,9 cases had partial seizures,6 cases had secondarily generalized seizures,5 cases had generalized seizures and 3cases had mental retardation.EEG showed heavy abnormal in 1 cases,medial abnormal in 8 cases and light abnormal in 5 cases.CT/MRI showed Subependymal heterotopia in 4 patients,subcortical heterotopia in 7 patients,band heterotopia in 1 patient and both Subependymal and Subcortical heterotopia in 2 patients.Conclusion Partial seizures might be more preponderant in patient with gray matter heterotopia and epilepsy.EEG results are significantly consistent with CT/MRI in judging the presence of local focus in patients with gray matter heterotopia.

关 键 词：脑灰质异位症 癫痫 脑电描记术 磁共振成像 体层摄影术 X线计算机 

分 类 号：R742.1[医药卫生—神经病学与精神病学]