乳酸清除率对危重新生儿预后的评估研究  

Evaluating Values of Lactate Clearance Rate in Prognosis of Critically Ill Newborns

作　　者：张雪梅[1] 

机构地区：[1]河南省安阳市妇幼保健院,455000

出　　处：《中国全科医学》2011年第18期2074-2075,共2页Chinese General Practice

摘　　要：目的探讨乳酸清除率对危重新生儿预后的评估价值。方法回顾性分析50例危重新生儿,收集入院时、治疗后6 h的动脉血乳酸值,计算6 h乳酸清除率,并与其24 h预后做相关性分析。结果将6 h乳酸清除率以50%和25%为界分组,6 h乳酸清除率>50%组24例,25%<6 h乳酸清除率≤50%组26例,6 h乳酸清除率≤25%组10例。3组患者预后情况比较,差异有统计学意义(P<0.05)。根据预后不同将患者分为3组,好转组患者6 h乳酸清除率(61.25±1.65)%较多脏器功能障碍综合征(MODS)组的(32.21±8.41)%和死亡组的(7.21±9.32)%均明显升高,差异有统计学意义(P<0.05);MODS组6 h乳酸清除率较死亡组亦明显升高,差异有统计学意义(P<0.05)。结论早期乳酸清除率是判断危重新生儿预后的较好指标。Objectives To explore the evaluating values of lactate clearance rate in prognoses of critically ill newborns.Methods Fifty cases of critically ill newborns were analyzed retrospectively and arterial blood lactate values were collected on admission and 6 h after treatment,6 h lactate clearance rate calculated,24 h prognosis analyzed correlatively.Results Six-hour lactate clearances were divided into groups A（6 h lactate clearance 50%,n=24）,B（6 h lactate clearance ≤50%,n=26） and C（6 h lactate clearance ≤25%,n=10）.There was significant difference in prognosis between 3 groups（P0.05）.The patients were divided by prognosis into groups improvement,multiple organ failure syndrome（MODS） and death.The 6 h lactate clearance was higher in group improvement than in groups MODS and death[（61.25±1.65）%,（32.21±8.41）%,（7.21±9.32）%,respectively],the difference was significant（P0.05）,and higher in group MODS than in death group（P0.05）.Conclusions The early lactate clearance rate is a good indicator for prognosis of critically ill newborns.

关 键 词：乳酸 危重病 婴儿 新生 预后 

分 类 号：R722.1[医药卫生—儿科]