饱中枢在针刺减肥中的作用研究  

Research on the Effect of Satiety Center in the Reduction of Weight by Electropuncture

作　　者：苏静[1] 刘志诚[2] 赵玫[2] 

机构地区：[1]中国人民解放军第454医院,210002 [2]南京中医药大学,210029

出　　处：《上海针灸杂志》1999年第6期30-31,共2页Shanghai Journal of Acupuncture and Moxibustion

基　　金：国家自然科学基金

摘　　要：目的　探讨针刺减肥的中枢机制。　方法　观察针刺对ＳＤ大鼠食源性肥胖模型的摄食量、肥胖指标和各部脂肪量的作用，并通过脑立体定位和神经细胞微电极记录技术，观察实验大鼠下丘脑腹内侧核（ＶＭＨ）电活动的变化。　结果　对照组的摄食量、肥胖指标及脂肪量显著高于正常组，针刺组摄食量、肥胖指标及脂肪量显著降低；对照组ＶＭＨ自发放电频率显著低于正常组，针刺组ＶＭＨ 自发放电频率显著高于对照组。　结论　提示饱中枢的激活可能是针刺产生减肥效应的途径之一。Objective To investigate the central mechanism of the reduction of body weight by electropuncture. Methods Observation was carried out of the effect of electropuncture on food intake, obesity indices and adipose amounts in different parts in SD rat model of food\|induced obesity and of changes in electric activities of ventromedial nucleus(VMH) of rat hypothalamus by cerebral stereotaxis and neurocyte microelectrode recording. Results Food intake, obesity indices and adipose amount were significantly higher in control group than in normal group. Food intake, obesity indices and adipose amount markedly dropped in acupuncture group. VMH spontaneous discharge frequency was significantly lower in control group than in normal group. VMH spontaneous discharge frequency was significantly higher in acupuncture group than in control group. Conclusion The excitation of satiety center may be one of the ways that acupuncture produces a reducing effect on body weight.

关 键 词：针刺效应 肥胖 饱中枢 

分 类 号：R259.892[医药卫生—中西医结合] R246.1[医药卫生—中医内科学]