胆管癌的腔内近距离治疗(附14例分析)  

Intraluminal Brachytherapy on Bile Duct Carcinoma: An Analysis of 14 Cases

作　　者：胡国清[1] 袁响林[1] 黄河[1] 

机构地区：[1]同济医科大学附属同济医院肿瘤科,武汉430030

出　　处：《同济医科大学学报》1999年第6期559-560,共2页Acta Universitatis Medicinae Tongji

摘　　要：自1991年3月至1997年12月，对14例不能手术的胆管癌进行了腔内近距离治疗，其中12例为肝门部胆管癌。腔内治疗采用高剂量率192Ir，剂量参考点距施源器中心轴的距离是10～12mm，参考点剂量为每次700～1000cGy，共3～5次。近距离照射总量为2800～4000cGy。治疗后的平均生存时间为11．2月。1、2、3、4年生存率分别为42．9％（6／14），33．3％（4／12），25．0％（2／8）和16．7％（1／6）、无严重的副反应。提示，腔内近距离治疗为不能手术切除的胆管癌提供了一种副作用小而疗效较好的治疗手段，提高了患者的生存质量，延长了生存时间。Fourteen patients with inoperable bile duct carcinoma were subjected to the treatment of intraluminal brachytherapy from March 1991 to Dec. 1997. Among the 14 cases, 12 patients were diagnosed having hilar bile duct carcinoma. High dose rate 192Ir was used for intraluminal brachytherapy. The reference point distance from the central axis of applicator varied from 10 to 12 mm. The reference point dose ranged from 700to 1000 cGy in each fraction and the total dose was ranged from 2800 to 4000 cGy. The average survival was 11. 2 months following brachytherapy. The 1-, 2-, 3m, 4-year survival rate was 42. 9 % (6/14), 33. 3 % (4/ 12), 25 % (2/8) and 16. 7 % (1/6), respectively. The results demonstrated intraluminal brachytherapy for inoperable bile duct carcinoma was effective, improve the quality of life in the majority of cases and prolong the survival.

关 键 词：胆管癌 近距离治疗 放射疗法 

分 类 号：R735.805[医药卫生—肿瘤] R730.55[医药卫生—临床医学]