胰腺神经内分泌癌的诊断及外科治疗(附10例临床报告)  

Diagnosis and surgical treatment of pancreatic neuroendocrine carcinoma(A report of 10 cases)

作　　者：刘骞[1] 黄帅[1] 刘剑坡[1] 白晓枫[1] 赵东兵[1] 单毅[1] 赵平[1] 

机构地区：[1]中国医学科学院肿瘤医院腹部外科,北京100021

出　　处：《实用肿瘤杂志》2011年第3期262-265,共4页Journal of Practical Oncology

摘　　要：目的探讨胰腺神经内分泌癌的诊断和外科治疗方法。方法回顾性分析外科手术治疗的10例胰腺神经内分泌癌的临床病理资料。结果本组10例均经手术病理证实,无1例通过术前检查诊断。1例于肿瘤切除术后30月死亡;术后迄今9例生存;2例未能切除肿瘤经术中放疗和化疗,生存11、17月。肿瘤切除组生存>20月2例,34月1例,>40月2例,50月1例,66月1例。结论胰腺神经内分泌癌术前诊断困难,对疑似病例应进行激素检测。胰腺神经内分泌癌应积极手术治疗,无法手术切除应积极进行化疗、化疗栓塞以延长生存时间。Objective To assess the diagnosis and the therapeutic methods of pancreatic neuroendocrine carcinoma. Methods Ten patients with pancreatic neuroendoerine carcinoma were underwent surgery and the clinical pathological data of 10 cases were analyzed. Results The diagnosis of 10 cases were confirmed by pathological examination, but none were diagnosed before operation. One case died 30 montds after the resection, 9 survived and 2 cases who underwent IORT and chemotherapy survived 11 and 17 months. Two cases survived more than 20 months, 1 survived 34 months, 2 survived more than 40 months, 1 survived 50 months, 1 survived 66 months. Conclusions Preoperative diagnosis is very difficult, hormone level should he tested in those patients who are suspected to be suffered from pancreatic neuroendocrine carcinoma. Surgery should be the first choice. If surgery can not he performed, chemotherapy and transeatheter arterial chemoembolization should be considered.

关 键 词：胰腺肿瘤/外科学 胰腺肿瘤/诊断 神经内分泌瘤/治疗 预后 

分 类 号：R735.9[医药卫生—肿瘤]