正畸加载时机及持续时间对自体移植牙牙周修复影响的组织学研究  

Histological study about the effect of orthodontic loading time and duration on the periodontal repair in autologous tooth transplantation

作　　者：孙慧芳[1] 刘毅[1] 郭泾[1,2] 陈扬熙[3] 

机构地区：[1]山东大学口腔医院正畸科,济南250012 [2]四川大学华西口腔医院正畸科,成都610041 [3]四川大学华西口腔医院口腔疾病研究国家重点实验室,四川大学,成都610041

出　　处：《华西口腔医学杂志》2011年第3期237-241,共5页West China Journal of Stomatology

基　　金：中国博士后科学基金资助项目(20090451410);山东省科技攻关基金资助项目(2008GG30002007)

摘　　要：目的建立犬自体牙移植动物模型,研究正畸加载时机及持续时间对自体移植牙牙周修复的影响。方法选取12只Beagle犬随机分组,选取每只犬的4颗第一前磨牙进行自体移植,分别在其自体牙移植手术后2、4、8和12周开始正畸加载,正畸加载持续时间分别为1、2和4周,并对其相应第一前磨牙牙体牙周组织标本进行组织学研究,测量牙根吸收率,统计学分析牙周组织的改建状况。结果实验组正畸加载移植牙牙根吸收率比对照组无正畸加载移植牙牙根吸收率低,经配对t检验,两者差异有统计学意义(P<0.05);不同加力持续时间(X)及加载时间点(Y)间移植牙牙根吸收率的差异均无统计学意义(P值均>0.05),但这2个因素间析因实验分析表明,2个因素间存在交互作用(X×Y的P值<0.05)。结论正畸力加载有助于移植牙牙根吸收状况的改善和牙周组织改建;加力持续时间及加载时间点对移植牙牙根吸收率的影响差异不明显。移植后4周开始正畸加载,加载持续2周时最有助于移植牙牙周组织的改建。Objective The study established an animal model of autologous tooth transplantation in dogs and aimed to explore the effects of orthodontic loading time and duration on the periodontal repair in autologous tooth transplantation.Methods 12 Beagle dogs were selected and grouped randomly in this research.Four first premolar teeth in every dog were carried on autologous transplant operation.These teeth were exerted the orthodontic force after the operation in 2,4,8 and 12 weeks respectively.The loading duration was 1,2 and 4 weeks respectively.We examined the dental and periodontal tissue samples in first premolar teeth by histological study,measured root absorption rate and analyzed reconstruction condition of periodontal tissue with statistical methods.Results Root absorption rates of the experimental group which was exerted the orthodontic force were lower than those of the control group.The difference between two groups had statistical significance（P0.05）.Root absorption rates in different levels of orthodontic loading time（X） and the duration（Y） had no statistical significance（P0.05）,but these two factors had interaction effect（PX×Y0.05）.Conclu-sion Orthodontic force contributes to the improvement of root absorption and reconstruction of periodontal tissue in transplant teeth.The orthodontic loading time and the duration have no obvious effect on root absorption rate of trans-plant teeth.When X is two weeks and Y is four weeks,it is most beneficial for the reconstruction effect of periodontal tissues in transplant teeth.

关 键 词：正畸加载 自体移植牙 牙周修复 

分 类 号：R783.5[医药卫生—口腔医学]