学龄儿童锌、硒、铜、铁摄入水平对抗氧化能力的影响  

EFFECT OF DIETARY ZN,SE,CU,FE LEVELS ON ANTI-OXIDATIVE CAPACITY IN SCHOOL-AGE CHILDREN

作　　者：唐咏梅[1] 舒畅[1] 宁鸿珍[1] 周瑞华[1] 李碧[1] 

机构地区：[1]华北煤炭医学院预防医学系,唐山063000

出　　处：《现代预防医学》2011年第13期2471-2472,2474,共3页Modern Preventive Medicine

基　　金：河北省医学科学研究重点课题计划资助项目(08178)

摘　　要：[目的]探讨膳食微量元素摄入影响儿童抗氧化能力的作用水平。[方法]选择唐山市3所小学382名1～6年级学生进行一般情况、食物摄取频率和膳食调查,经家长知情同意后采静脉血测定其抗氧化酶和过氧化产物水平;营养计算器V1.6转换数据,SPSS11.5软件进行分析。[结果]当锌摄入水平在80%推荐摄入量(RNI)以下时,受影响的血清SOD低于参考值,MDA水平高于参考值;当硒摄入水平在100%RNI以下时,受影响的血清MDA水平高于参考值,在140%RNI以下时,GSH-Px低于参考值;当铜摄入水平在100%RNI以下时,受影响的血清MDA水平高于参考值,在140%RNI以下时,SOD低于参考值;当铁摄入水平在150%适宜摄入量(AI)以下时,受影响的血清MDA水平高于参考值,在200%AI以下时,SOD低于参考值。[结论]当锌摄入量≥80%RNI、硒与铜摄入量≥140%RNI、铁摄入量≥200%RNI时,儿童体内抗氧化指标水平达到正常;需要通过调整膳食结构及必要时的补充干预,提高儿童体内抗氧化能力。[Objective]To study effect of microelements intake levels on antioxidant activity in children.[Methods]Totally 382 students from 1-6 grades were investigated about their general state of health,5 days diet and 1 month food frequency.Serum vitamin,antioxidant enzymes and peroxidation product were determined after being informed to parents.The intakes were transformed with nutrition calculator V1.6.The data were analyzed with SPSS11.5 software.[Results]When zinc（Zn）intakes were below 80% of reference nutrient intake（RNI）,the level of serum SOD was lower than normal level,MDA was higher than normal level.When selenium（Se）intake was below 100% of RNI,the level of serum MDA was higher than normal level.When Se intake was below 140% of RNI,GSH-Px was lower than normal level.When cupper（Cu）intake was below 100% of RNI,the level of serum MDA was higher than normal level.When Cu intake was below 140% of RNI,SOD was lower than normal level.When iron（Fe）intake was below 150% of adequate intake（AI）,the level of serum MDA was higher than normal level.When Fe intake was below 200% of AI,SOD was lower than normal level.[Conclusion]Children＇s antioxidant levels are normal when their intakes of Zn﹥80% of RNI,Se﹥140 of RNI,Cu﹥140% of RNI,and Fe﹥200% of AI.It is necessary to improve dietary or microelements supplementation for children,so as to enhance their anti-oxidative capacity.

关 键 词：学龄儿童 微量元素 摄入量 抗氧化 回归分析 

分 类 号：R153.2[医药卫生—营养与食品卫生学]