颅脑损伤后抑郁的发生情况及影响因素研究  

STUDY ON DEPRESSION CAUSED BY TRAUMATIC BRAIN INJURY AND ITS INFLUENCING FACTORS

作　　者：刘建民[1] 孙鸿[2] 黄良文[1] 胡鹏[1] 戴先才[1] 

机构地区：[1]广州中医药大学第一附属医院颅脑科,广州510405 [2]四川大学华西医院神经外科

出　　处：《现代预防医学》2011年第13期2535-2536,2538,共3页Modern Preventive Medicine

摘　　要：[目的]探讨颅脑损伤后抑郁的发生情况以及与影响抑郁发生的相关因素。[方法]收集2005年1月～2010年1月在某院住院康复治疗的脑外伤患者共200名,采用自制问卷调查收集患者的人口学资料,以及和抑郁发生的相关因素。采用卡方检验和Logistic回归分析影响抑郁的因素。[结果]抑郁在颅脑损伤病人中的发生率为56.00%,其中,抑郁发生于性别、文化程度、受伤当时的意识状态GCS得分、有无经济赔偿、外伤后EQ-5D评分有相关性。Lo-gistic回归发现,有无经济赔偿,GCS得分以及外伤后日程生活活动测评和生命质量测评分对患者预后是否会患抑郁的影响最大,OR值分别为5.25(2.74～10.10),4.23(2.24～8.04)和4.89(2.55～9.48)。[结论]颅脑损伤患者容易发生抑郁,其发生情况与患者的预后生命质量和经济支持有明显关系。[Objective]To explore the situation of depression and its influencing factors among traumatic brain injury（IBI）patients.[Methods]A total of 200 traumatic brain injury patients were collected from January 2005 to January 2010,and self-designed questionnaire was used to collect the demographic data and its influencing factors on depression.Chi-square test and Logistic regression were used to analyze its influencing factors.[Results]The incidence of depression in TBI patients was 56.00%,and the influencing factors were related to sex,culture degree,GCS score,economic compensation and EQ-5D after IBI.The Logistic regression found the economic compensation,GCS score and quality of life after injury had the highest OR of depression,and the ORs were 5.25（2.74-10.10）,4.23（2.24-8.04）and 4.89（2.55-9.48）,respectively.[Conclusion]BI patients are likely to have depression,and its incidence has correlation with quality of life as well as economic support.

关 键 词：颅脑损伤 抑郁 创伤预后 

分 类 号：R749.41[医药卫生—神经病学与精神病学]