蛛网膜下腔出血血清与脑脊液NO、CGRP、脑微区血流量及CRP水平变化研究  

STUDY OF SERUM AND CEREBROSPINAL FLUID NO,CGRP,CRP AND MICRO-REGIONAL CEREBRAL BLOOD FLOW IN THE PATIENTS WITH SUBARACHNOID HEMORRHAGE

作　　者：郝彬[1] 赵红果[1] 

机构地区：[1]郑州市第二人民医院神经外科,郑州450052

出　　处：《现代预防医学》2011年第13期2592-2593,共2页Modern Preventive Medicine

摘　　要：[目的]探讨蛛网膜下腔出血血清与脑脊液NO、CGRP、脑微区血流量及CRP变化规律。[方法]选取2008年1月～2010年1月进行治疗的20例蛛网膜下腔出血患者为观察组,同时选取20名健康人为对照组,后将两组人员的血清与脑脊液NO、CGRP、脑微区血流量及CRP水平进行研究及比较。[结果]经研究及比较发现,观察组的血清与脑脊液NO、CGRP低于对照组,而血清与脑脊液CRP水平高于对照组,脑微区血流量低于对照组,两组比较,P均﹤0.05,差异均有统计学意义。[结论]蛛网膜下腔出血血清与脑脊液NO、CGRP、脑微区血流量及CRP水平变化对于了解其预后及转归有一定的作用,值得临床进一步研究探讨。[Objective]To study the regulation of serum and cerebrospinal fluid NO,CGRP,CRP and micro-regional cerebral blood flow in the patients with subarachnoid hemorrhage.[Methods]20 patients with subarachnoid hemorrhage in our hospital from January 2008 to January 2010 were selected as observation group,and 20 healthy people were selected as control group,then the levels of serum and cerebrospinal fluid NO,CGRP,CRP and micro-regional cerebral blood flow of the two groups were detected and compared.[Results]The levels of serum and cerebrospinal fluid NO and CGRP of the observation group were lower than those of the control group,but the levels of serum and cerebrospinal fluid CRP of the observation group were higher than those of the control group.Micro-regional cerebral blood flow of the observation group was loss than that of the control group,P﹤0.05,there were significant differences.[Conclusion]The changes of serum and cerebrospinal fluid NO,CGRP,CRP and micro-regional cerebral blood flow in the patients with subarachnoid hemorrhage plays a role for investigating the prognosis,and is worthy of further study.

关 键 词：蛛网膜下腔出血 NO CGRP 脑微区血流量 CRP 

分 类 号：R743.35[医药卫生—神经病学与精神病学]