间变性星形细胞瘤的MRI特点  

MRI Findings of Anaplastic Astrocytoma

作　　者：陈耿[1] 韩立新[1] 曹慧霞[1] 王俊[1] 

机构地区：[1]广州军区广州总医院磁共振室,广州510010

出　　处：《肿瘤防治研究》2011年第6期682-684,共3页Cancer Research on Prevention and Treatment

摘　　要：目的探讨间变性星形细胞瘤(AA)的MRI表现特点,研究MRI对该类肿瘤的诊断要点与诊断价值。方法回顾性分析12例经手术病理证实的间变性星形细胞瘤(WHOⅢ级)的MRI影像特点。结果肿瘤多位于额叶(50%),可呈多发病灶表现(1例);肿瘤多呈囊实性改变(83.33%),实性部分与灰质信号相比呈等T1、稍长T2信号,FLAIR呈稍高信号,增强扫描呈不规则环形明显强化;主要累及皮层,相邻白质受累,病变大者占位效应重、水肿重,内有坏死或钙化,边界不清,周围组织受压明显,中线结构偏移,但病变很少向对侧大脑半球侵犯;多发病灶病例表现缺乏特异性。结论 MRI能清楚地显示病变的范围和特点,具有一定的诊断和鉴别诊断价值。Objective To investigate the MR imaging features and diagnostic points of anaplastic astrocytoma.Methods MR studies of 12 patients with pathologically confirmed anaplastic astrocytomas（WHO Ⅲ grade） were reviewed retrospectively.Results The tumors were mainly located in frontal lobe（50%）,and 1 case presented multiple lesions.The tumors showed the performance of cystic-solid（83.33%）.Compared with gray matter,solid part has a signal of iso-intensity in T1WI and slight hyper-intensity in T2WI and FLAIR,with an obviously irregular ring enhancement.The tumors were mainly located in the cortex and involved the white matter.Those tumors with large lesions exhibited necrosis or calcification inside them,heavily mass effect,peripheral edema,bad-demarcated border,and obviously oppressed surrounding tissue,offset the midline;while those tumors were rarely not overpassed to the contralateral hemisphere.The case of multiple lesions showed unspecific performance.Conclusion MRI can clearly detect the extent and feature of anaplastic astrocytoma and should be the first modality of choice in showing the tumor spectrum,which has a significant clinical value for the diagnosis of anaplastic astrocytoma and for the differential diagnosis.

关 键 词：星形细胞瘤 间变性 磁共振成像 

分 类 号：R739.41[医药卫生—肿瘤]