高铜日粮对肉鸡肝脏抗氧化功能的影响  

Effect of Different Levels of Dietary Copper Sulfate on Liver Antioxidantal Index in Broilers

作　　者：胡锴[1] 任常宝[1] 颜城[1] 苏荣胜[1] 郭剑英[1] 潘家强[1] 唐兆新[1,2] 

机构地区：[1]华南农业大学兽医学院,广东广州510642 [2]广东省兽用生物制品技术研究与应用企业重点实验室,广东新兴527400

出　　处：《中国家禽》2011年第12期26-29,共4页China Poultry

基　　金：国家自然科学基金资助项目(30871900)

摘　　要：选用1日龄健康商品代AA肉鸡200只随机分成4组,使用硫酸铜作为铜源,饲喂玉米-豆粕型基础日粮,对照组饲料铜含量为11mg/kg,3个试验高铜组饲料铜含量分别为110、330和550mg/kg,试验至50日龄结束,探讨高铜日粮对肉鸡肝脏超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)、总抗氧化能力(T-AOC)、过氧化氢酶(CAT)、丙二醛(MDA)含量的影响。结果显示:110、330和550mg/kg组T-AOC、SOD和GSH-Px活性先呈代偿性升高,后表现降低,而CAT和MDA分别表现为代偿性下降和升高。表明日粮铜含量为330mg/kg及其以上可引起肝脏抗氧化功能受损,最终导致肝脏功能紊乱。The effect of high level dietary copper on the liver mitochondrial super oxide dlsmutase（SOD）,glutathione peroxidase（GSH-Px）,total antioxidation capacity（T-AOC）,catalase（CAT）,malonaldehyde（MDA） in broiles was investigated in this study. 200 1-day-age healthy AA broilers were divided into four groups randomly. Based on the control group （11 mg/kg Cu）,three experimental groups were set up, they were 110,330,550 mg/kg Cu,respectively. All of the experimental broilers were fed with corn-soybean meal containing copper for 50 days. The results showed that T-AOC,SOD,GSH-Px in high level copper （110,330,550 mg/kg） groups were compensatory and then decreased,CAT was decreased compensatorily and MDA was increased compensatorily. The results demonstrated that dietary copper content of 330 mg/kg and above could damaged liver anti-oxidation and cause liver dysfunction.

关 键 词：铜 肉鸡 肝脏 抗氧化功能 

分 类 号：S831.5[农业科学—畜牧学]