基于溶血性能的离心式旋转血泵设计  

Design of Centrifugal Blood Pump Based on Hemolysis Estimation

作　　者：阮晓东[1] 陈松松[1] 钱伟文[2] 邹俊[1] 付新[1] 

机构地区：[1]浙江大学流体传动及控制国家重点实验室,杭州310027 [2]浙江省人民医院心胸外科,杭州310000

出　　处：《中国生物医学工程学报》2011年第3期411-415,共5页Chinese Journal of Biomedical Engineering

基　　金：国家高技术研究发展(863)计划(2010AA045401);中央高校基本科研业务费专项资金资助(2009QNA4001)

摘　　要：溶血性能是衡量血泵性能的一个重要指标。基于平均剪切应力模型,通过减少红细胞流经叶轮的时间和降低它在此过程中所受平均剪切应力的方法,对离心血泵进行设计,进而改善溶血性能。采用商用流体仿真软件Fluent,对血泵内的三维不可压湍流流场进行数值模拟,得到红细胞在血泵内的流动迹线和流动参数;应用溶血估算公式,分析不同流量下血泵的溶血性能,计算得到溶血估算值在0.006～0.015之间,有较好的溶血性能,满足血泵对溶血性能的要求。Hemolytic performance is an important index of blood pump.Based on average shear stress model,we optimized the parameters of the impeller to reduce the time of red blood cells flowing through the impeller and the average shear stress they suffered in the process.Computational fluid dynamic simulations of the flow in the centrifugal blood pump were used in the present study.The traces and flow parameters of red cells in the blood pump were acquired.With the help of empirical formulas of hemolysis,hemolytic performances of pump in different flow rates were acquired.The predicted blood damage index was between 0.006 and 0.015,which showed that hemolysis performance of the blood pump is satisfactory.In conclusion the design method for blood pump is applicable.

关 键 词：离心式旋转血泵 溶血估算 计算流体力学 

分 类 号：R318.01[医药卫生—生物医学工程]