采用一种新型动态力加载装置研究力对镍铬烤瓷合金中镍离子释放的影响  

Influence of occlusal force on Ni release from Ni-Cr PFM alloys by designing a novel device with dynamic occlusal loads

作　　者：刘贤[1] 孙皎[1] 

机构地区：[1]上海交通大学医学院附属第九人民医院上海生物材料研究测试中心上海市口腔医学重点实验室,上海200011

出　　处：《医用生物力学》2011年第3期247-251,共5页Journal of Medical Biomechanics

基　　金：上海市重点学科建设项目(S30206)

摘　　要：目的设计一种新型动态力加载装置,研究力对镍铬烤瓷合金中镍离子释放的影响。方法依据人咀嚼的平均力(45 N)和频率(80次/min)设计一种动态力加载装置。运用该装置研究3种常用镍铬烤瓷合金(上齿牌、Stellite、BEGO)分别在pH 2.3和pH 7.0的人工唾液中镍离子的释放量。结果新型动态力加载装置能够模拟咀嚼频率进行人体平均力的加载。当pH 2.3时,上齿牌、Stellite和BEGO 3种镍铬烤瓷合金镍离子释放量分别为6.9(2.07)μg/cm2、3.7(0.662)μg/cm2和5.88(1.57)μg/cm2;当pH 7.0时,分别为0.272(0.059)μg/cm2、0.144(0.014)μg/cm2和0.435(0.053)μg/cm2。同种镍铬烤瓷合金材料在pH 2.3的人工唾液中镍离子的释放量均远大于在pH 7.0环境下的释放量,两者具有显著的统计学差异(P<0.01)。结论动态力加载装置可有效地被用于体外研究力对镍离子释放的影响。酸性环境可明显加快镍铬烤瓷合金中镍离子释放。本研究中Stellite镍铬烤瓷合金释放的镍离子量相对最少。Objective To design a novel device with dynamic occlusal loads so as to investigate the influence of occlusal force on Ni release from Ni-Cr PFM alloys.Methods Based on the average force（45 N） and rate（80 cycles/min） of human mastication,a novel device with dynamic occlusal loads was designed to study the Ni release from three commonly used Ni-Cr PFM alloys（Shangchi,Stellite,BEGO） in the artificial saliva with pH 2.3 and pH 7.4,respectively.Results This novel device with dynamic occlusal loads worked well to simulate the average force and chewing cyclye.In the artificial saliva with pH 2.3,the amount of Ni release in Shangchi,Stellite and BEGO was 6.9（2.07） μg/cm2,3.7（0.662） μg/cm2 and 5.88（1.57） μg/cm2,respectively;while in the artificial saliva with pH 7.0,the amount of Ni release in Shangchi,Stellite and BEGO was 0.272（0.059） μg/cm2,0.144（0.014） μg/cm2 and 0.435（0.053） μg/cm2,respectively.For the same Ni-Cr PMF alloys,the amount of Ni release in the artificial saliva with pH 2.3 was much higher than that with pH 7.0（P0.01）,showing statistical differences.Conclusions The device with dynamic occlusal loads could be used effectively to evaluate the influence of occlusal force on Ni release from Ni-Cr PFM alloys in vitro.The acid environment could obviously accelerate the Ni release from Ni-Cr PFM alloys.This study showed the amount of Ni release in Stellite was relatively lower than that in the other two alloys.

关 键 词：力 动态加载 合金 镍离子释放 

分 类 号：R783.2[医药卫生—口腔医学]