早期抗抑郁治疗对急性脑梗死并发抑郁患者神经功能恢复的影响  

Effects of early anti-depression therapy on the neurological function of patients in acute cerebral infarction with depression

作　　者：郑姣琳[1] 肖兴军[1] 王维治[1] 

机构地区：[1]哈尔滨医科大学附属第二医院神经内科,黑龙江哈尔滨150081

出　　处：《哈尔滨医科大学学报》2011年第2期163-164,167,共3页Journal of Harbin Medical University

摘　　要：目的评价早期抗抑郁治疗对急性脑梗死并发抑郁患者神经功能恢复的影响。方法将70例急性脑梗死合并抑郁患者随机分成治疗组和对照组。两组均采用急性脑梗死的常规治疗,治疗组在常规治疗的基础上给予氟西丁晨起20 mg顿服,采用中国脑卒中患者临床神经功能缺损程度评分标准,对治疗后第7天,第14天患者进行疗效评估。结果 7天及14天治疗组的神经功能缺损程度评分显著低于对照组(P<0.05)。秩和检验显示治疗组的恢复程度显著优于对照组(P<0.05)。结论早期抗抑郁治疗可促进急性脑梗死并发抑郁患者神经功能的恢复。Objective To evaluate the influence of anti-depression therapy on the rehabilitation of neurological function in patients suffering acute cerebral infarction with post-stroke depression in early stage.Methods Seventy patients were divided into treatment group and control group randomly.Patients in treatment group received routine therapy and Fluoxetine,and patients in control group received routine therapy only.The efficacy of the treatment at 7 and 14d were evaluated by clinical neurological deficit scores.Results The neurological function deficit scores of the treatment group at 7 and 14d were significantly lower than those of the control group（P0.05）.The rank sum test indicated that the efficacy of the treatment group were obviously superior to that of the control group（P0.05）.Conclusion The treatment for patients in acute cerebral infarction with post-stroke depression in early stage is effective for the rehabilitation of neurological function.

关 键 词：卒中后抑郁 急性脑梗死 氟西丁 

分 类 号：R749.13[医药卫生—神经病学与精神病学] R743.33[医药卫生—临床医学]