渗出性年龄相关性黄斑变性341例激光治疗效果分析(英文)  

Laser treatment in 341 patients with exudative age-related macular degeneration

作　　者：Leyla Atmaca Aysun Idil Pelin Atmaca-Snmez 

机构地区：[1]土耳其安卡拉私人诊所眼科 [2]土耳其安卡拉大学医学院低视力康复研究中心公共卫生系 [3]土耳其安卡拉Nurlu眼科中心

出　　处：《国际眼科杂志》2011年第7期1132-1136,共5页International Eye Science

摘　　要：目的:探讨渗出性年龄相关性黄斑变性( AMD) 患者激光治疗的预后。方法:前后比较,以评价治疗的有效性。结果:共纳入341 例392 眼渗出性 AMD 病例,其中77.6%伴有脉络膜新生血管( CNV) 。未使用吲哚氰绿( ICG) 血管造影时,仅在 1. 8% 患眼发现隐匿性 CNV; 而使用 ICG血管造影后,该比例提高到 19. 5% ( P < 0. 001) 。激光治疗后,共 349 眼进入随访,其中 68. 2% 视力保持稳定。经统计学检验,病变部位与治疗前后视力改变相关( P <0. 001) ,也与病变复发相关( P < 0. 05) 。在黄斑中心凹区病变的复发率小于旁中心凹或中心凹外病变。结论:ICG 血管造影对研究隐匿性 CNV 治疗效果相当重要。AIM：To document the prognosis of laser treatment in patients with exudative age-related macular degeneration （AMD）.METHODS：Efficacy of the intervention was evaluated using a before-after method.RESULTS：A total of 392 eyes of 341 patients with exudative AMD were examined.77.6% had choroideal neovascularisation （CNV）.Before the use of indocyanine green （ICG） angiography,occult CNV was detected in only 1.8% of the eyes,but after the use of ICG angiography,this increased to 19.5% （P〈0.001）.Of the 349 eyes which were followed up,visual acuity had remained stable in 68.2% of the eyes.There was a statistically significant relationship between localization of lesion and visual acuity changes on pre-and post-laser treatment （P〈0.001）.Also there was a statistically significant relationship between localization of lesion and recurrence （P〈0.05）.The recurrence was less in subfoveal lesions than that in juxtafoveal and extrafoveal lesions.CONCLUSION：ICG angiography is highly important in the treatment of occult CNV.

关 键 词：氪红激光 氩绿激光 染料激光 渗出性年龄相关性黄斑变性 吲哚氰绿血管造影 

分 类 号：R774.5[医药卫生—眼科]