胎盘绒毛膜血管瘤3例临床病理分析  

Placental chorioangioma:a clinicopathologic analysis of three cases

作　　者：陈倩[1] 向吉富[1] 彭英霞[1] 杨博[1] 

机构地区：[1]吉首大学第一附属医院病理科,湖南吉首416000

出　　处：《诊断病理学杂志》2011年第3期226-228,共3页Chinese Journal of Diagnostic Pathology

摘　　要：目的探讨胎盘绒毛膜血管瘤的临床和病理特点、诊断和鉴别诊断,提高对该肿瘤的认识。方法对3例胎盘绒毛膜血管瘤进行临床病理和免疫组化观察,并进行文献分析。结果镜下表现为大量增生的毛细血管样血管,局灶血管扩张呈海绵状血管瘤样,伴有黏液变、凝固性坏死及钙化,瘤细胞CD34(+)。结论胎盘绒毛膜血管瘤是一种少见的胎盘良性肿瘤,病理形态类似于其他部位的血管瘤,常常引起羊水过多、胎儿水肿、心功能衰竭、贫血等症状,但目前尚无规范的处理方法。Objective To explore the clinical and pathological characteristics,diagnosis,differential diagnosis of placental chorioangioma and to improve awareness of it.Methods The clinicopathological changes and immunohistochemical findings in three cases of chorioangioma were observed with review of the related literature.Results Microscopically,the tumors were made up of a lot of proliferative capillary with mucoid degeneration,coagulative necrosis and calcification in some fields,and some lumens were distended just like cavernous hemangioma.The tumor cells were positive for CD34.Conclusion Chorioangioma is a rare benign tumor in placenta.Its pathologic features are similar to the hemangioma in other parts of the body.It is often complicated by polyhydramnios,fetal hydrops,congestive heart failure and anaemia.But now we have not had specifications about the treatment of this tumor.

关 键 词：胎盘 绒毛膜血管瘤 病理 

分 类 号：R737.33[医药卫生—肿瘤]