激素联合血浆交换治疗格林巴利综合征疗效分析  

Effect of Methylprednisolone impulsion plus plasma exchange for Guillain-Barre Syndrome

作　　者：李晶[1] 闫海清[1] 

机构地区：[1]河南省卫辉市新乡医学院第一附属医院小儿内三科,453100

出　　处：《中国实用医药》2011年第17期48-49,共2页China Practical Medicine

摘　　要：目的观察激素联合血浆交换治疗格林巴利综合征疗效。方法对入院的24例格林巴利综合征患者采用分组对照观察,其中观察组应用甲基强地松龙冲击联合血浆交换治疗组12例,对照组应用血浆交换治疗。治疗20d后比较不同治疗方案对格林巴利综合征的疗效。结果两组患者在治疗20d后病情均有好转,观察组疗效与对照组比较疗效差异有统计学意义(P<0.05)。结论甲基强地松龙冲击联合血浆交换对格林巴利综合征疗效均明显优于单纯血浆交换治疗,效果显著,值得临床推广。Objective To observe the therapeutic effect of methylprednisolone impulse with plasma exchange on Guillain-Barre syndrome. Methods Twenty-four patients with Guillain-Barre syndrome were randomly divided into two groups（observation gruop and control group）：12 patients were treated with plasma exchange alone, 12 with both intravenous Methylprednisolone and plasma exchange.The clinical efficacy was evaluated by clinical improvement from baseline by at least one grade on a seven-point scale of motor function Twenty days after the treatment. Results Two groups of patients condition had improved after treatment, observation group was significant difference between the two groups（P〈0.05）. Conclusion The therapeutic efficacy of Methylprednisolone plus and plasma exchange are significantly better than that of plasma exchange alone. Its clinical application is effective and convenient.It is worthy of clinical application.

关 键 词：格林巴利综合征 血浆交换 激素冲击 治疗 

分 类 号：R745.43[医药卫生—神经病学与精神病学]