胸腺肽α1对脑梗死患者院内获得性肺炎的预防作用  

Preventive effect of thymosin alpha1 on nosocomial pneumonia in patients with acute cerebral infarction

作　　者：王志海[1] 陈颖[1] 

机构地区：[1]湛江中心人民医院神经内科,广东湛江524037

出　　处：《海南医学院学报》2011年第7期926-928,共3页Journal of Hainan Medical University

基　　金：海南医学院科研基金资助学报项目(0020110232)~~

摘　　要：目的:探讨胸腺肽α1对脑梗死患者院内获得性肺炎的预防作用。方法:将58例急性大脑中动脉脑梗死患者随机分为2组:胸腺肽α1治疗组及常规治疗组。于治疗前、后观察患者院内获得性肺炎发生率并测定患者C反应蛋白浓度、白细胞计数,进行疗效评价。结果:胸腺肽α1治疗组患者院内获得性肺炎发生率较常规治疗组低(P<0.05),而且治疗后治疗组患者的C反应蛋白、白细胞计数恢复显著(P<0.05)。结论:胸腺肽α1对脑梗死患者院内获得性肺炎有预防作用。Objective： To investigate the preventive effect of thymosin alpha1 on nosocomial pneumonia in patients with acute cerebral infarction.Methods： A total of 58 patients with acute cerebral infarction were randomly divided into two groups： thymosin alpha 1 group and control group.The incidence of nosocomial pneumonia,the level of C-reactive protein（CRP） and white blood cell（WBC） count were observed and compared.Result： The incidence rate of sonocomial pneumonia was significantly lower（P〈0.05）,and the level of CRP and WBC count were improved significantly in thymosin alpha 1 group（P〈0.05）.Conclusions： Thymosin alpha1 can prevent cerebral infarction patients from nosocomial pneumonia.

关 键 词：胸腺肽Α1 脑梗死 院内获得性肺炎 

分 类 号：R743[医药卫生—神经病学与精神病学]