息肉状脉络膜血管病变在眼底FFA与ICGA中特征分析  

Comparison on fundus fluorescein angiography and indocyanine green angiography in polypoidal choroidal vasculopathy

作　　者：于爱萍[1] 肖云[1] 张改丽[1] 李明[1] 徐四俊[1] 

机构地区：[1]解放军第474医院眼科医院全军眼科中心,乌鲁木齐830013

出　　处：《中国实用眼科杂志》2011年第7期722-724,共3页Chinese Journal of Practical Ophthalmology

摘　　要：目的探讨息肉状脉络膜血管病变（PCV）H~底荧光素血管造影（FFA）和吲哚青绿血管造影（ICGA）同步检查的影像学特征及其临床意义。方法选取62例患者（75只眼）进行眼底彩色照相、FFA和ICGA同步检查，对黄斑部视网膜下出血病灶其形态及特征做以对比分析。结果FFA图像显示：PCV75只眼中斑块样视网膜下出血48只眼，占64．0％；伴浆液性视网膜色素上皮（RPED）脱离12只眼，占16．0％；出血性RPED8只眼，占10．7％；脉络膜血管网及息肉样结节7只眼，占9．4％，早期即出现荧光素渗漏并逐渐增强，CNV末端膨大处出现点状高荧光。ICGA图像显示：75只患眼中72只眼呈“蘑菇”状或“树枝”状异常扩张，其血管网末端多个息肉样膨大与彩色照相所见的结节样病变部位吻合。结论FFA和ICGA同步检查，不但对PCV患者病灶其形态及特征作出对比分析，ICGA检查还能提高PCV视网膜下脉络膜新生血管膜（CNV）的检出率，同时提高PCV患者激光光凝的可能性，而FFA对评估PCV视网膜下出血及出血性或浆液性视网膜色素上皮脱离、脉络膜血管网及息肉状结节则均有较好的效果。Objective To observe on fundus fluorescein angiography （FFA） and indocyanine green angiography （ICGA） in polypoidal choroidal vasculopathy （PCV）, and sync examine of its image features and clinical meaning. Methods Sixty-two patients （75 eyes） applied fundus camera, FFA and ICGA synchronous examination, do comparison analysis in macular sub-retinal hemorrhage shape and area. Results FFA image in 75 PCV patients showed 48 eyes （64.0%） with plaque sub-retinal hemorrhage, 12 eyes （16.0%） accompanied with retinal pigment epithelial detachments （RPED）, 8 eyes （10.7%） with bleeding RPED, 7 eyes （9.4%） with choroid blood vessel net and polypoidal node of early stage flouresence leakage. ICGA showed that 75 eyes had abnormal choroid blood vessel net extension, 72 with ＂mushroom＂ shape or ＂tree-branch＂ shape with more polypoidal enlarge in the end which was the same as seen under ophthalmoscope. Conclusions It proves that FFA and ICGA synchronous examination, not only can be used for PCV patients＇ tissue shape and area comparison analysis, but also improves the finding rate of the choroidal neovascularization （CNV） in PCV, increases the feasibility of photocoagulation to PCV. FFA gives good result to evaluate PCV sub-retinal hemorrhage.

关 键 词：脉络膜病变 荧光素血管造影 吲哚花青绿/诊断应用 

分 类 号：R773.4[医药卫生—眼科]