薄层及全厚口腔黏膜移植术治疗睑球粘连的临床观察  

A clinical study of lameller and full-thickness mouth mucosa transplantation for symblepharon

作　　者：梁申芝[1] 孔宇[1] 袁军[1] 陈鹏[1] 

机构地区：[1]郑州市第二人民医院眼科郑州市眼科医院,郑州450003

出　　处：《中国实用眼科杂志》2011年第7期725-727,共3页Chinese Journal of Practical Ophthalmology

摘　　要：目的探讨薄层及全厚口腔黏膜移植治疗睑球粘连的疗效。方法采用薄层口腔黏膜移植术治疗14只眼睑球粘连患者，全厚口腔黏膜移植术12只眼，将薄层或全厚口腔黏膜置于结膜缺损处，7／0缝线将其固定于结膜游离创面，行结膜囊成形术。结果两组睑球粘连均得到分离（14／14，12／12），移植的薄层及全厚口腔黏膜均成活，结膜囊重建满意（14／14，12／12），但全厚组的移植物呈红色不透明，患者美观满意度差（4／12）。薄层组移植物呈淡粉红色半透明，患者美观满意度较好（11／14）。结论薄层或全厚口腔黏膜移植治疗睑球粘连均是一种行之有效的手术方法，但薄层组更美观。Objective To evaluate the effects of transplantation of mouth mucosa for symblepharon. Methods Fourteen eyes of symblepharon were treated with lameller mouth mucosa transplantation, and 12 eyes were treated with full-thickness mouth mucosa transplantation. The mouth mucosa was flattened onto the conjunctival defect, the mucosa was secured to surrounding conjunctival edge with 7/0 nylon sutures. Results Surgery successfully released the symblepharon of the two groups （14/14, 12/12）. All mouth mucosa gratis were alive during a 6-12 months follow-up. The operation of reconstruction of conjunctival sac for all eyes was successful （14/14, 12/12）. The full-thickness mouth mucosa group appeared red and opacity, the lameller mouth mucosa group showed pale pink and semitransparent. The patient＇s satisfaction degree in the full-thickness group （4/12） was worse than the lameller group （11/14）. Conclusions Transplantation of lameller and full-thickness mouth mucosa appears to be a promising surgical treatment for reconstructing the ocular surface in patients with symblepharon. The thansplantation of lameller is more perfect.

关 键 词：薄层口腔黏膜 全厚口腔黏膜 移植 睑球粘连 

分 类 号：R781.5[医药卫生—口腔医学]