肠易激综合征与肠道细菌关系的研究进展  

Advances in understanding the relationship between irritable bowel syndrome and intestinal bacteria

作　　者：舒小闯[1] 王少东[1] 汪芳裕[1] 

机构地区：[1]南京大学医学院临床学院(中国人民解放军南京军区南京总医院)消化内科,江苏省南京市210002

出　　处：《世界华人消化杂志》2011年第17期1808-1812,共5页World Chinese Journal of Digestology

摘　　要：肠易激综合征(irritable bowel syndrome,IBS)是一种复杂的多因素功能性疾病,其病因和发病机制尚未明确.肠道共生菌与宿主和平共处,互惠互利,这种关系破坏直接或间接参与宿主多种疾病的发生与发展.近年来,随着微生态学的发展,肠道菌群与IBS发病的关系日益受到关注.大量研究显示,肠道细菌与IBS关系密切.本文主要就IBS时肠道菌群的变化及肠道细菌参与IBS发病的可能机制予以综述.Irritable bowel syndrome （IBS） is a multifactorial functional disorder of unknown cause and pathophysiology. Commensal bacteria in the digestive tract and host co-exist in a mutually beneficial relationship. If this relationship is interrupted, various types of diseases will be caused. In recent years, the development of microecology has led to a better understanding of the relationship between intestinal bacterial flora and IBS. Many studies have suggested a close relationship between intestinal bacteria and IBS. In this article, we will review the role of alterations in intestinal bacterial flora in the pathogenesis of IBS.

关 键 词：肠易激综合征 肠道细菌 微生态失调 

分 类 号：R574[医药卫生—消化系统]