平阳霉素治疗颌面部静脉畸形及囊性水瘤的临床体会  

Vascular Malformations and Lymphatic Malformations in Maxillofacial Region Treated by Pinyangmycin

作　　者：马力强 周晓霖 陈辉 

机构地区：[1]抚顺市中心医院口腔科,辽宁抚顺113006

出　　处：《口腔颌面外科杂志》2011年第3期201-202,共2页Journal of Oral and Maxillofacial Surgery

基　　金：辽宁省百千万工程资助项目(2007LRC186)

摘　　要：目的:探讨应用平阳霉素治疗颌面部静脉畸形及囊性水瘤的疗效。方法:22例颌面部静脉畸形患者,6例囊性水瘤患者,用平阳霉素配以适量地塞米松及利多卡因,在静脉畸形及囊性水瘤的瘤腔内注射,开始应用平阳霉素为4 mg/次,2～3周后再次应用可达8 mg/次,每次复诊均复查血常规、凝血功能及肝功。病变瘤腔内注药3～4次为一疗程。结果:经2年随访观察,16例静脉畸形患者及4例囊性水瘤患者病变消失;另6例静脉畸形及2例囊性水瘤患者病变明显缩小,3年后病变持续缩小接近消失。结论:应用平阳霉素瘤腔内注射治疗静脉畸形及囊性水瘤是一种简便且有效的方法。Objective： To summarize the clinical approaches of Pinyangmycin in treating of vascular and lymphatic malformation in head and neck.Methods： 28 patients were retrospectively reviewed.Pinyangmycin mixed with dexamethsone and lidocaine was injected in focus of vascular malformation and lymphatic malformation.Pinyangmycin first injection was 4mg.8mg Pinyangmycin was used again after two or three weeks,which could be repeated 3-4 times.Blood routine examination,stagnant blood and liver functions were checked each time.Results： Vascular malformation in 16 patients and lymphatic malformation in 4 patients were observed and completely faded away after 2-year follow-up.Vascular malformation in 6 patients and lymphatic malformation in 2 were partially decreased,and almost fade away at the end of three-year.Conclusion： Injecting Pinyangmycin at the center of vascular and lymphatic malformation was simple and effective.

关 键 词：平阳霉素 血管畸形 囊性水瘤 颌面部 

分 类 号：R739.8[医药卫生—肿瘤]