蒙特利尔认知量表中文版诊断老年轻度认知功能损害的应用研究  

Exploration of the Chinese version montreal cognitive assessment in the diagnosis of mild cognitive impairment

作　　者：高中宝[1] 王炜[1] 尚延昌[1] 柏秀娟[1] 吴卫平[1] 

机构地区：[1]解放军总医院南楼临床部神经内科,北京100853

出　　处：《中华保健医学杂志》2011年第3期225-227,共3页Chinese Journal of Health Care and Medicine

基　　金：中央保健专项资金科研课题(B2009B104);南楼临床部青年创新基金课题(NO201108)

摘　　要：目的探讨蒙特利尔认知量表(Montreal cognitive assessment,MoCA)中文版诊断老年轻度认知功能损害(mildcognitive impairment,MCI)的效能。方法选取73例MCI患者为MCI组和51例认知功能正常者为对照组,对两组进行均衡性检验及MoCA中文版评估。结果 MCI组MoCA总分、视空间功能、命名、计算力、语言、抽象及延迟回忆项得分显著低于对照组(P<0.01);以26分作为分界值,MoCA中文版诊断MCI结果与Petersen诊断标准结果相比较,差异无统计学意义(P=0.289),诊断符合率为0.935、敏感度为0.918、特异度为0.961、阳性预测值为0.971、阴性预测值为0.961。结论 MoCA中文版适于MCI患者的早期筛查和初步诊断。Objective To explore the usage of the Chinese version of Montreal Cognitive Assessment（MoCA） in mild cognitive impairment （MCI）. Methods Seventy-three patients with mild cognitive impairment were selected as MCI group and fifty-one adults with normal cognition as control group. Consistency checking and the Chinese version of MoCA were performed. Results The score of MoCA and its subitems including Visuospatial skill,denomination ,calculation ,language ,abstract ability and delay recall in MCI group were significantly lower than control（P〈0.01 ）. Using a cutoff score of 26,MCI could be diagnosed by MoCA with no differ- ence from Petersen criteria（P=-0.289）,with coincidence as 0.935, sensitivity as 0.918, specificity as 0.961 ,positive predictive value as 0.971 ,and negative predictive value as 0.961. Conclusions The Chinese version of MoCA is suitable to the screening and diagnosis of MCI at early stage.

关 键 词：蒙特利尔认知量表 轻度认知功能损害 认知评估 诊断 

分 类 号：R743[医药卫生—神经病学与精神病学]