中枢神经系统白血病影像诊断  

Imaging diagnosis of leukemia of the central nervous system

作　　者：明小春[1] 杨万群[2] 黄飚[2] 梁长虹[2] 

机构地区：[1]湛江中心人民医院CT、MR室,广东524037 [2]广东省人民医院放射科,广州510080

出　　处：《放射学实践》2011年第6期590-592,共3页Radiologic Practice

摘　　要：目的:回顾性分析经临床证实的7例中枢神经系统白血病的CT和MRI表现,提高对该病的诊断水平。方法:中枢神经系统白血病7例均是男性,急性淋巴细胞白血病3例,急性髓性白血病3例,慢性粒细胞白血病急性变1例。5例患者CT平扫后行MRI检查;其余2例患者未作CT扫描,直接行MRI平扫及增强检查。结果:①白血病浸润软脑膜3例,其中2例同时浸润视神经鞘膜;②脑实质受浸润3例,其中病变呈片状浸润脑实质2例,1例合并出血;脑实质内形成肿块1例;③硬脑膜受累1例,左颞硬脑膜形成肿块,累及左颞骨及左颞软组织;④脊髓受浸润1例,病变广泛浸润胸段脊髓。结论:结合病史,MRI检查有助于对中枢神经系统白血病的诊断,对其进展及疗效观察均有重要价值。Objective：To improve the level of the diagnosis,the CT and MRI findings of 7 cases with clinically confirmed leukemia of the central nervous system were retrospectively analysed.Methods：All seven patients were male.There were consist of 3 cases with acut lymphocytic leukemia,3 cases with acut nonlymphocytic leukemia and one case with chronic granulocytic leukemia in this study.Five patients were performed MRI after plain CT;two patients underwent MRI only.Results：①There was infiltration of leptomeninges in three cases,also with involvement of optic nerve in two cases;②Parenchyma was invaded in 3 cases,including the patchy lesions in parenchyma in 2 cases,with hemorrhage in 1 case;and tumor-like lesions in 1 case;③Dura mater was involved in 1 case.There was a high-density mass（granulocytic sarcomas） on the left dura mater with bone and soft tissue involvement;④There was involvement of spinal cord in one case,the thoracic spinal cord was diffusely infiltrated.Conclusion：Combining with the history MRI is a useful tool for helping in the diagnosis of the leukemia of the central nervous system.

关 键 词：中枢神经系统 白血病 体层摄影术 X线计算机 磁共振成像 

分 类 号：R733.7[医药卫生—肿瘤] R814.42[医药卫生—临床医学]