^(99m)Tc-MIBI亲肿瘤显像鉴别甲状腺结节良恶性的临床价值  

The Value of Tumor Avid Imaging with 99mTc-MIBI in the Differential Diagnosis for Thyroid Nodules

作　　者：胡疏[1] 韦伟[2] 尹为华[3] 高宙[1] 陈清[1] 孙雯[1] 樊蓉[1] 贾少微[2] 

机构地区：[1]北京大学深圳医院核医学科,广东深圳518036 [2]北京大学深圳医院甲状腺乳腺外科,广东深圳518036 [3]北京大学深圳医院病理科,广东深圳518036

出　　处：《罕少疾病杂志》2011年第3期7-9,共3页Journal of Rare and Uncommon Diseases

摘　　要：目的探讨99mTc-MIBI亲肿瘤显像在甲状腺结节良恶性鉴别中的价值。方法对492例甲状腺结节患者进行甲状腺99mTcO4-显像及99mTc-MIBI双时相显像,随后患者均接受外科手术治疗并作病理检查。分析99mTc-MIBI甲状腺亲肿瘤显像结果与病理检查的符合程度。结果 99Tcm-MIBI显像对甲状腺结节性质良恶性鉴别的敏感度、特异度和准确度分别为60.35%、80.88%和76.37%,阳性似然比3.15,阴性似然比0.49。结论甲状腺99Tcm-MIBI亲肿瘤显像对于甲状腺癌的诊断具有一定的临床参考价值。Objective To evaluate the value of tumor avid imaging with 99mTc-MIBI in the differential diagnosis for thyroid nodules.Methods 492 patients with thyroid nodules were examined by thyroid 99mTcO4-imaging and two-phase 99mTc-MIBI imaging.All the patients underwent surgical operation and pathological demonstration.The coincidence of the thyroid imaging estimations and the pathological reports was analyzed subsequently.Results The sensitivity,specificity,accuracy,positive likelihood ratio and negative likelihood ratio of the differential diagnosis of thyroid nodules by 99mTc-MIBI imaging were 60.35%,80.88%,76.37%,3.15,and 0.49 separately.Conclusion Tumor avid imaging with 99mTc-MIBI may be valuable for the differential diagnosis of thyroid nodules.

关 键 词：甲状腺结节 99m锝-甲氧基异丁基异腈 亲肿瘤显像 

分 类 号：R730.41[医药卫生—肿瘤]