ADC值在后颅窝髓母细胞瘤与室管膜瘤鉴别诊断中的价值研究  

The Value of Differentiation between Posterior Fossa Medulloblastomas and Ependymomas with ADC Value

作　　者：刘建雄[1] 曹代荣[1] 邢振[1] 庄碧梅[1] 刘颖[1] 丁雅玲[1] 

机构地区：[1]福建医科大学附属第一医院影像科,福建福州350005

出　　处：《中国CT和MRI杂志》2011年第3期5-7,共3页Chinese Journal of CT and MRI

摘　　要：目的探讨ADC值对后颅窝髓母细胞瘤与室管膜瘤鉴别诊断的价值。资料与方法回顾性分析手术病理证实的9例髓母细胞瘤和5例室管膜瘤的ADC图像,全部病例均行常规MR平扫+增强扫描、DWI成像,ADC值测定感兴趣区(ROI)置于病灶强化最明显且在ADC图上呈相对低信号部位,取病灶最小ADC值,对同一病例以相同大小ROI置于正常大脑白质区测量三个ADC值,取其平均值。相对ADC值(rADC)取病灶最小ADC值与正常大脑白质区平均ADC值的比值,对两组病例的ADC值和rADC值分别行Wilcoxon秩和检验。结果髓母细胞瘤测得的最小ADC值范围为0.49-0.74×10-3mm2/s,rADC值范围为0.61-1.09;室管膜瘤测得的最小ADC值范围为0.80-0.92×10-3mm2/s,rADC值范围为0.91-1.14。髓母细胞瘤与室管膜瘤最小ADC值范围没有重叠。髓母细胞瘤与室管膜瘤间的最小ADC值及rADC值差异均有统计学意义(P<0.05)。结论 ADC值的测量可以准确鉴别后颅窝髓母细胞瘤与室管膜瘤。Objective To evaluate value for differentiating posterior fossa medulloblastomas from ependymomas with apparent diffusion coefficient（ADC）.Methods Fourteen patients with histologically proved posterior fossa tumor were reviewed restrospectively.There were 9 medulloblastomas,5 ependymomas.All patients were examined with conventional MRI,enchanced MRI and diffusion weighted imaging（DWI）.Region of interest（ROI） were draw on low signal regions of apparent diffusion coefficient（ADC） maps in enchancing tumor.The lowest ADC values and rADCwere recorded.The ADC values and rADC values in medulloblastomas were compared with those in ependymomas as by using Wilcoxon rank sum test.Results The range of minADC values on medulloblastomas and ependymomas were 0.49-0.74＊10-3mm2/s and 0.80-0.92＊10-3mm2/s,the range of rADC values were 0.61-1.09 and 0.91-1.14.There were no overlap in individual tumor minADC values between medulloblastomas and ependymomas.ADC and rADC values were marked different on medulloblastomas and ependymomas（P0.05）.Conclusion Assessment of ADC values can differentiate medulloblastomas from ependymomas accurately.

关 键 词：表观扩散系数 髓母细胞瘤 室管膜瘤 

分 类 号：R73[医药卫生—肿瘤] R445.2[医药卫生—临床医学]