烟用香料大柱三烯酮的合成  

Synthesis of Tobacco Fragrant Component Megstigmatrienone

作　　者：陈恩治 

机构地区：[1]爱普香料集团股份有限公司,上海201809

出　　处：《北京工商大学学报（自然科学版）》2011年第3期16-19,共4页Journal of Beijing Technology and Business University:Natural Science Edition

摘　　要：以α-异佛尔酮为原料,经异构得到β-异佛尔酮;后者与三甲基氯硅烷在碘化钠催化下醚化反应得到β-异佛尔酮三甲基硅烷烯醇醚,再与巴豆醛经Aldol反应合成了重要烟用香料大柱三烯酮,产品经GC-MS鉴定,总得率35%,含量为75%.β-isophorone was obtained from α-isophorone via isomerization, which was then reacted with trimethylchlorosilane using sodium iodide as the catalyst to get β-isophorone trimethylsilyl enol ether. Af- ter Aldol reaetion with erotonaldehyde, the important Tobacco fragrant component Megstigmatrienone was synthesized. The structure of the product was identified by GC-MS. The Overall yield was 35% , the con- tent was 75 %.

关 键 词：α-异佛尔酮 三甲基氯硅烷 β-异佛尔酮三甲基硅烷烯醇醚 巴豆醛 大柱三烯酮 

分 类 号：TS201.2[轻工技术与工程—食品科学] TS201.1[轻工技术与工程—食品科学与工程]