对比增强前后SWI在脑星形细胞肿瘤分级中的诊断价值  

The diagnostic value of pre-and post-contrast susceptibility weighted imaging(SWI) in grading brain astrocytic tumors

作　　者：郑兆凤[1] 董光[2] 王琦[2] 耿海[2] 郑岗[2] 谭绪平[2] 

机构地区：[1]潍坊医学院医学影像学系,山东潍坊261042 [2]潍坊医学院附属潍坊市人民医院放射科,山东潍坊261042

出　　处：《医学影像学杂志》2011年第6期797-800,共4页Journal of Medical Imaging

摘　　要：目的:探讨对比增强前后磁共振磁敏感加权成像(susceptibility weighted imaging,SWI)在脑星形细胞肿瘤分级中的应用价值。方法:选取手术病理证实前均行磁共振传统序列及SWI序列扫描的28例星形细胞肿瘤患者,观察肿瘤成像特点并进行比较;对SWI图像ITSS分级,分析其与肿瘤术后病理学分级之间的关系。结果:28例病灶,低级别组10例(Ⅰ级2例,Ⅱ级8例),高级别组18例(Ⅲ级10例,Ⅳ级8例)。18例病灶内显示ITSS,低级别组10例仅2例Ⅱ级肿瘤ITSS分级为1级,余均为0级;高级别组ITSS分级较高,8例多形性胶质母细胞瘤ITSS分级均为3级,间变性星形细胞瘤中2例ITSS分级为0级,3例为1级,3例为2级,2例为3级。ITSS分级和星形细胞肿瘤病理学级别的Spearman相关系数为0.854。结论:SWI序列作为传统序列的有效补充,增强前后SWI图像清晰显示瘤内出血和静脉血管,有助于肿瘤分级的评定,对于指导临床治疗和评估预后具有重要意义。Objective：To estimate the diagnostic value of pre-and post-contrast-enhanced susceptibility-weighted imaging（SWI） in grading brain astrocytic tumors.Methods：A total of 28 patients（11 women,17 men） with brain astrocytic tumors included in this study.In addition to conventional magnetic resonance imaging,pre-and post-contrast-enhanced SWI were performed in all patients,whose images were analyzed between them.The intratumoral susceptibility signal intensity（ITSS） on SW images was graded,then correlation with the pathological gradation done.Results：To tally 28 tumors were found,and the number of low and high-grade tumors is 10（grade Ⅰ 2,grade Ⅱ8） and 18（grade Ⅲ 10,grade Ⅳ 8）.ITSSs were found in 18 tumors,which included 2 low-grade tumors and 16 high-grade tumors.The grade of ITSS of the two low-grade tumors and 8 glioblastomas is 1 and 3,but the grade of ITSS of anaplastic astrocytomas is variable（the number of ITSS scale 0,1,2,3 is 2,3,3,1 respectively）.Spearman correlation coefficient between ITSS scale and pathological gradation was 0.854.Conclusion：SWI clearly revealed the intratumoral blood production and small veins of astrocytic tumors,which may be instructive for clinical treatment and prognosis.

关 键 词：磁共振成像 磁敏感加权成像 星形细胞肿瘤 

分 类 号：R739.4[医药卫生—肿瘤] R445.2[医药卫生—临床医学]