霉菌性食管炎79例内镜特点及临床分析  

Endoscopic Features and Clinical Analysis of 79 Mycotic Esophagitis

作　　者：孔令亭[1] 杨海燕[1] 甄玉青[1] 

机构地区：[1]山东省烟台市烟台山医院消化内科,264000

出　　处：《中华全科医学》2011年第8期1230-1231,F0003,共3页Chinese Journal of General Practice

摘　　要：目的提高对霉菌性食管炎内镜特点和临床表现认识,指导临床用药。方法对79例霉菌性食管炎的临床表现、发病诱因及相关疾病、内镜表现及治疗结果进行分析。结果霉菌性食管炎内镜主要表现是散在白斑及糜烂,发病诱因及相关疾病较多,与抗生素的大量使用关系密切,且发病率逐年增高,目前常用的抗霉菌类药疗效较好。结论霉菌性食管炎有多种上消化道症状,但无特异性。内镜是诊断该病的重要手段,确诊要靠细胞刷涂片找霉菌,对内窥镜检查发现食管炎应注意真菌检测,尤其对H.pylori(幽门螺杆菌)感染与消化道疾病相关患者使用抗生素者应重点检测。目前抗霉菌药物对霉菌性食管炎的疗效较满意,胃镜下管道刷刷洗治疗霉菌性食管炎简单、安全,且无副作用,值得临床推广。Objective To improve the understanding of endoscopic features and clinical analysis, and to direct the clinical use of drugs. Methods The clinical manifestations, pathogenesis and related diseases, and endoscopic manifestation and treatment results of mycotic esophagitis were analyzed. Results The common endoscopic signs were diffuse leukoplakia or erosion. Patho- genesis and related diseases were increasing, and incidence was related to the use of antibiotics, infection rates increased year by year and currently used antifungus drugs were effective. Conclusion There were many symptoms of mycotic esophagitis but clini- cal manifestations were nonspecific, gastroendoscopic examination was of great＂value for the clinical dianosis of mycotic esophagi- tis, while etiological analyses should be made for confirmed diagnosis. Gastroendoscopie examination should be pay attention to the fungal detection, especially for H. pylori infection and digestive disorders related patients who used antibiotic. Currently used anti- fungus drugs were effective, the treatment of mycotic esophagitis by endoscopic tube cleaning brush was safe and effective.

关 键 词：霉菌性食管炎 内镜特点 临床分析 

分 类 号：R571[医药卫生—消化系统]