利用Perkin反应制备香豆素的实验探析  

Exploration on experiment of synthesis coumarin by using Perkin reaction

作　　者：高庆[1] 

机构地区：[1]扬州工业职业技术学院,江苏扬州225127

出　　处：《实验室科学》2011年第3期75-78,共4页Laboratory Science

摘　　要：从反应机理、反应影响因素出发,对Perkin反应合成香豆素的反应过程、反应装置、分离过程分别进行了探讨。实验表明,该反应在N2保护下时可以得到更高的合成收率,实验成功的关键在于试验装置设计较为合理,而实验过程中所体现的实验技能正是培养学生实验技能的良好案例。This article discusses separately the process,the installation,and the separation process of the Perin reaction on the basis of the reaction mechanism and the influencing factors correlated,which is used in synthesizing coumarin.The experiment shows that higher yield rate might be obtained under the protection of N2.The key to success of the experiment lies in reasonable design of the reaction installation,and the experiment is a good case in training students＇experimental skills,which is reflected in the process of the experiment.

关 键 词：Prekin反应 香豆素 实验探析 

分 类 号：R914.5[医药卫生—药物化学]