滋阴清热生津法对糖尿病动物模型的干预研究  

Intervention Research of the Treatment Principle of Nourishing Yin,Clearing Heat and Generating Fluid on Animal Models of Diabetes Mellitus

作　　者：韩颖萍[1] 黄霞[1] 袁效涵[1] 刘惠霞[1] 孙为[1] 

机构地区：[1]河南省中医药研究院,河南郑州450004

出　　处：《中医学报》2011年第6期694-695,共2页Acta Chinese Medicine

基　　金：河南省科技厅预研基金项目(编号:0641130506)

摘　　要：目的:观察滋阴清热生津法对糖尿病动物模型的干预研究。方法:采用SD大鼠分别灌胃给药,Alx复制出糖尿病动物模型,比较各组大鼠体质量,检测血清GLU、INS水平。结果:采用滋阴清热生津法可显著降低模型动物血清GLU水平,对模型动物体质量下降有拮抗作用,与模型组相比差异均具有显著性意义(P<0.05)。提高模型大鼠血清Ins水平,但无统计学意义。结论:滋阴清热生津法对糖尿病模型动物血清GLU高水平和体质量下降具有拮抗作用,对模型大鼠血清Ins水平具有升高趋势。Objective：To observe the intervention research of the treatment principle of nourishing yin,clearing heat and generating fluid on animal model of diabetes mellitus.Methods：SD rats were given gavage;animal model of diabetes mellitus were replicated through Alx;body weights of rats in each group were compared and serum levels of GLU and INS were detected.Results：Serum levels of GLU in animal models could be significantly reduced by the treatment principle of nourishing yin,clearing heat and generating fluid,which had antagonistic effects on the weight loss of animal models.Compared with the model group,differences were significant（P0.05）.There was no statistical significance to enhance the serum levels of INS.Conclusion：The treatment principle of nourishing yin,clearing heat and generating fluid has antagonistic effects on serum GLU levels and weight loss of animal models of diabetes mellitus,showing a trend of increasing serum levels of INS.

关 键 词：滋阴清热生津法 药物作用 GLU INS 

分 类 号：R285.5[医药卫生—中药学]