粪肠球菌生物膜细胞外聚合物的研究进展  

Research progress on extracelluar matrix in Enterococcus faecalis biofilm

作　　者：黎卫兰[1] 徐琼[1] 

机构地区：[1]中山大学光华口腔医学院.口腔医学研究所,广州510055

出　　处：《国际口腔医学杂志》2011年第4期426-429,共4页International Journal of Stomatology

基　　金：广东省科技计划基金资助项目(2009B030801115;20-10B050700007)

摘　　要：粪肠球菌是根管治疗后再感染的主要致病菌,常以生物膜的形式存在。包绕在细菌周围或黏附在细菌表面的糖类、核酸和分泌蛋白对粪肠球菌的初始黏附、生物膜空间结构和细菌间信息交流等起重要的作用。本文就粪肠球菌生物膜及其细胞外聚合物组分和去除方法作一综述。Enterococcus faecalis is a predominant organism that plays a major role in the etiology of persistent periradicular lesions after root canal treatment by forming biofilms.The matrix,which holds bacterial biofilms together,is a complex mixture of macromolecules including expolysaccharides,nucleic acid and protein.Extracelluar matrix contributes significantly to bacterial adhesion,biofilm structure and information exchanging between bacterias.This review mainly focused on the bioflim structure,extracelluar matrix and ways to eliminate the Enterococcus faecalis biofilm.

关 键 词：粪肠球菌 生物膜 细胞外聚合物 

分 类 号：R780.2[医药卫生—口腔医学]